VB 11328

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341607

CAS#: 160231-42-5

Description: VB 11328 is a biochemical.


Price and Availability

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Price

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VB 11328 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 341607
Name: VB 11328
CAS#: 160231-42-5
Chemical Formula: C28H38N2O7S
Exact Mass: 546.24
Molecular Weight: 546.679
Elemental Analysis: C, 61.52; H, 7.01; N, 5.12; O, 20.49; S, 5.86


Synonym: VB 11328; VB-11328; VB11328.

IUPAC/Chemical Name: Carbamic acid, ((1S,2R)-3-((cyclopentylmethyl)((4-methoxyphenyl)sulfonyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-,(3S)-tetrahydro-3-furanyl ester

InChi Key: ZQUDHBMLXPGCHF-DOEKTCAHSA-N

InChi Code: InChI=1S/C28H38N2O7S/c1-35-23-11-13-25(14-12-23)38(33,34)30(18-22-9-5-6-10-22)19-27(31)26(17-21-7-3-2-4-8-21)29-28(32)37-24-15-16-36-20-24/h2-4,7-8,11-14,22,24,26-27,31H,5-6,9-10,15-20H2,1H3,(H,29,32)/t24-,26-,27+/m0/s1

SMILES Code: O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](O)CN(CC3CCCC3)S(=O)(C4=CC=C(OC)C=C4)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Pazhanisamy S, Partaledis JA, Rao BG, Livingston DJ. In vitro selection and characterization of VX-478 resistant HIV-1 variants. Adv Exp Med Biol. 1998;436:75-83. Review. PubMed PMID: 9561202.

2: Pazhanisamy S, Stuver CM, Cullinan AB, Margolin N, Rao BG, Livingston DJ. Kinetic characterization of human immunodeficiency virus type-1 protease-resistant variants. J Biol Chem. 1996 Jul 26;271(30):17979-85. PubMed PMID: 8663409.

3: Partaledis JA, Yamaguchi K, Tisdale M, Blair EE, Falcione C, Maschera B, Myers RE, Pazhanisamy S, Futer O, Cullinan AB, et al. In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease. J Virol. 1995 Sep;69(9):5228-35. PubMed PMID: 7636964; PubMed Central PMCID: PMC189353.