VFN38826
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 564123

CAS#: 1613638-82-6

Description: VFN38826, also known as CDK8-IN-4, is a CDK8 inhibitor. VFN38826 was first reported in patent WO2014090692A1, compound example 16, with an IC50 of 0.2 nM. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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VFN38826
CAS# 1613638-82-6
Instruction

Theoretical Analysis

MedKoo Cat#: 564123
Name: VFN38826
CAS#: 1613638-82-6
Chemical Formula: C20H18N4O
Exact Mass: 330.15
Molecular Weight: 330.390
Elemental Analysis: C, 72.71; H, 5.49; N, 16.96; O, 4.84

Price and Availability

Size Price Availability Quantity
5mg USD 450 2 Weeks
10mg USD 750 2 Weeks
25mg USD 1250 2 Weeks
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Synonym: CDK8-IN-4, VFN38826; VFN-38826; VFN 38826;

IUPAC/Chemical Name: (R)-2-((5-(1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylethan-1-ol; (2R)-2-[[5-(1H-Indazol-5-yl)pyridin-3-yl]amino]-2-phenylethanol

InChi Key: VFKCKMKPKIUZOF-FQEVSTJZSA-N

InChi Code: InChI=1S/C20H18N4O/c25-13-20(14-4-2-1-3-5-14)23-18-9-16(10-21-12-18)15-6-7-19-17(8-15)11-22-24-19/h1-12,20,23,25H,13H2,(H,22,24)/t20-/m0/s1

SMILES Code: OC[C@H](NC1=CC(C2=CC3=C(NN=C3)C=C2)=CN=C1)C4=CC=CC=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 330.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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