1,1,1-Trifluoroethyl-PEG5-Tos
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573019

CAS#: 1872433-61-8

Description: 1,1,1-Trifluoroethyl-PEG5-Tos is a PEG Linker.


Price and Availability

Size
Price

100mg
USD 450
Size
Price

250mg
USD 680
Size
Price

500mg
USD 1100

1,1,1-Trifluoroethyl-PEG5-Tos, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 573019
Name: 1,1,1-Trifluoroethyl-PEG5-Tos
CAS#: 1872433-61-8
Chemical Formula: C17H25F3O7S
Exact Mass: 430.1273
Molecular Weight: 430.44
Elemental Analysis: C, 47.44; H, 5.85; F, 13.24; O, 26.02; S, 7.45


Synonym: 1,1,1-Trifluoroethyl-PEG5-Tos

IUPAC/Chemical Name: 14,14,14-trifluoro-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate

InChi Key: UYAXEKCLHRTXQU-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H25F3O7S/c1-15-2-4-16(5-3-15)28(21,22)27-13-12-25-9-8-23-6-7-24-10-11-26-14-17(18,19)20/h2-5H,6-14H2,1H3

SMILES Code: O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCC(F)(F)F)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550.

2: Harrison E, Coulter JA, Dixon D. Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker. Nanomedicine (Lond). 2016 Apr;11(7):851-65. Review. PubMed PMID: 27021417.

3: Augusto MT, Hollmann A, Porotto M, Moscona A, Santos NC. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length. Molecules. 2017 Jul 15;22(7). pii: E1190. doi: 10.3390/molecules22071190. PubMed PMID: 28714870; PubMed Central PMCID: PMC5776016.

4: Tuma R, Russell M, Rosendahl M, Thomas GJ Jr. Solution conformation of the extracellular domain of the human tumor necrosis factor receptor probed by Raman and UV-resonance Raman spectroscopy: structural effects of an engineered PEG linker. Biochemistry. 1995 Nov 21;34(46):15150-6. PubMed PMID: 7578129.

5: Kanazaki K, Sano K, Makino A, Yamauchi F, Takahashi A, Homma T, Ono M, Saji H. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. doi:10.1016/j.jconrel.2016.02.017. Epub 2016 Feb 8. PubMed PMID: 26869546.