Zeylanan

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341397

CAS#: 20149-41-1

Description: Zeylanan is a biochemical.


Chemical Structure

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Zeylanan
CAS# 20149-41-1

Theoretical Analysis

MedKoo Cat#: 341397
Name: Zeylanan
CAS#: 20149-41-1
Chemical Formula: C17H18O6
Exact Mass: 318.1103
Molecular Weight: 318.325
Elemental Analysis: C, 64.14; H, 5.70; O, 30.16

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Zeylanan; Zeylanane.

IUPAC/Chemical Name: Zeylanan

InChi Key: ZJPVGXJXVIUSQM-SYFSXDBKSA-N

InChi Code: InChI=1S/C17H18O6/c1-8-6-12-13(9(2)7-20-12)14-15-17(23-15,16(19)22-14)5-4-11(8)21-10(3)18/h6-7,11,14-15H,4-5H2,1-3H3/b8-6+/t11-,14-,15+,17-/m0/s1

SMILES Code: C=1c2c(c(co2)C)[C@@H]2OC([C@@]3([C@@H]2O3)CC[C@@H](C1C)OC(C)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 318.325 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Wu KC, Ho YL, Kuo YH, Huang SS, Huang GJ, Chang YS. Hepatoprotective Effect of Ugonin M, A Helminthostachyszeylanica Constituent, on Acetaminophen-Induced Acute Liver Injury in Mice. Molecules. 2018 Sep 21;23(10). pii: E2420. doi: 10.3390/molecules23102420. PubMed PMID: 30241403.

2: Gunathilake KDPP, Ranaweera KKDS, Rupasinghe HPV. Effect of Different Cooking Methods on Polyphenols, Carotenoids and Antioxidant Activities of Selected Edible Leaves. Antioxidants (Basel). 2018 Aug 30;7(9). pii: E117. doi: 10.3390/antiox7090117. PubMed PMID: 30200223; PubMed Central PMCID: PMC6162770.

3: Gupta VK, Kaushik A, Chauhan DS, Ahirwar RK, Sharma S, Bisht D. Anti-mycobacterial activity of some medicinal plants used traditionally by tribes from Madhya Pradesh, India for treating tuberculosis related symptoms. J Ethnopharmacol. 2018 Dec 5;227:113-120. doi: 10.1016/j.jep.2018.08.031. Epub 2018 Aug 30. PubMed PMID: 30172059.

4: Li J, Wu H, Santana I, Fahlgren M, Giraldo JP. Standoff Optical Glucose Sensing in Photosynthetic Organisms by a Quantum Dot Fluorescent Probe. ACS Appl Mater Interfaces. 2018 Aug 29;10(34):28279-28289. doi: 10.1021/acsami.8b07179. Epub 2018 Aug 14. PubMed PMID: 30058800.

5: Arulmozhi P, Vijayakumar S, Kumar T. Phytochemical analysis and antimicrobial activity of some medicinal plants against selected pathogenic microorganisms. Microb Pathog. 2018 Oct;123:219-226. doi: 10.1016/j.micpath.2018.07.009. Epub 2018 Jul 19. PubMed PMID: 30009969.

6: Zaki AM, El-Tanbouly DM, Abdelsalam RM, Zaki HF. Plumbagin ameliorates hepatic ischemia-reperfusion injury in rats: Role of high mobility group box 1 in inflammation, oxidative stress and apoptosis. Biomed Pharmacother. 2018 Oct;106:785-793. doi: 10.1016/j.biopha.2018.07.004. Epub 2018 Jul 11. PubMed PMID: 29990872.

7: Hanan NA, Chiu HI, Ramachandran MR, Tung WH, Mohamad Zain NN, Yahaya N, Lim V. Cytotoxicity of Plant-Mediated Synthesis of Metallic Nanoparticles: A Systematic Review. Int J Mol Sci. 2018 Jun 11;19(6). pii: E1725. doi: 10.3390/ijms19061725. Review. PubMed PMID: 29891772; PubMed Central PMCID: PMC6032206.

8: Yamauchi K, Fujieda A, Mitsunaga T. Selective synthesis of 7-O-substituted luteolin derivatives and their melanonenesis and proliferation inhibitory activity in B16 melanoma cells. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2518-2522. doi: 10.1016/j.bmcl.2018.05.051. Epub 2018 May 28. PubMed PMID: 29887353.

9: Balamurugan S, Vijayakumar S, Prabhu S, Morvin Yabesh JE. Traditional plants used for the treatment of gynaecological disorders in Vedaranyam taluk, South India - An ethnomedicinal survey. J Tradit Complement Med. 2017 Jul 4;8(2):308-323. doi: 10.1016/j.jtcme.2017.06.009. eCollection 2018 Apr. PubMed PMID: 29736387; PubMed Central PMCID: PMC5934708.

10: Napagoda M, Gerstmeier J, Butschek H, Lorenz S, Kanatiwela D, Qader M, Nagahawatte A, De Soyza S, Wijayaratne GB, Svatoš A, Jayasinghe L, Koeberle A, Werz O. Lipophilic extracts of Leucas zeylanica, a multi-purpose medicinal plant in the tropics, inhibit key enzymes involved in inflammation and gout. J Ethnopharmacol. 2018 Oct 5;224:474-481. doi: 10.1016/j.jep.2018.04.042. Epub 2018 May 1. PubMed PMID: 29727733.

11: Pai SA, Martis EAF, Joshi SG, Munshi RP, Juvekar AR. Plumbagin exerts antiobesity effects through inhibition of pancreatic lipase and adipocyte differentiation. Phytother Res. 2018 Aug;32(8):1631-1635. doi: 10.1002/ptr.6085. Epub 2018 Apr 19. PubMed PMID: 29672969.

12: Gunathilake KDPP, Ranaweera KKDS, Rupasinghe HPV. Influence of Boiling, Steaming and Frying of Selected Leafy Vegetables on the In Vitro Anti-inflammation Associated Biological Activities. Plants (Basel). 2018 Mar 16;7(1). pii: E22. doi: 10.3390/plants7010022. PubMed PMID: 29547518; PubMed Central PMCID: PMC5874611.

13: Huang H, Xie H, Pan Y, Zheng K, Xia Y, Chen W. Plumbagin Triggers ER Stress-Mediated Apoptosis in Prostate Cancer Cells via Induction of ROS. Cell Physiol Biochem. 2018;45(1):267-280. doi: 10.1159/000486773. Epub 2018 Jan 22. PubMed PMID: 29357323.

14: Rajalakshmi S, Vyawahare N, Pawar A, Mahaparale P, Chellampillai B. Current development in novel drug delivery systems of bioactive molecule plumbagin. Artif Cells Nanomed Biotechnol. 2018 Jan 3:1-10. doi: 10.1080/21691401.2017.1417865. [Epub ahead of print] PubMed PMID: 29298523.

15: Gunasekara T, Radhika N, Ragunathan KK, Gunathilaka D, Weerasekera MM, Hewageegana H, Arawwawala LADM, Fernando S. Determination of Antimicrobial Potential of Five Herbs used in Ayurveda Practices against Candida albicans, Candida parapsilosis and Methicillin Resistant Staphylococcus aureus. Anc Sci Life. 2017 Apr-Jun;36(4):187-190. doi: 10.4103/asl.ASL_179_16. PubMed PMID: 29269969; PubMed Central PMCID: PMC5726184.

16: Messeha SS, Zarmouh NO, Mendonca P, Kolta MG, Soliman KFA. The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells. J Neuroimmunol. 2017 Dec 15;313:129-137. doi: 10.1016/j.jneuroim.2017.09.007. Epub 2017 Sep 20. PubMed PMID: 28950995; PubMed Central PMCID: PMC5696062.

17: Vu PT, Unpaprom Y, Ramaraj R. Impact and significance of alkaline-oxidant pretreatment on the enzymatic digestibility of Sphenoclea zeylanica for bioethanol production. Bioresour Technol. 2018 Jan;247:125-130. doi: 10.1016/j.biortech.2017.09.012. Epub 2017 Sep 5. PubMed PMID: 28946085.

18: Ito C, Matsui T, Takano M, Wu TS, Itoigawa M. Anti-cell proliferation effect of naphthoquinone dimers isolated from Plumbago zeylanica. Nat Prod Res. 2018 Sep;32(18):2127-2132. doi: 10.1080/14786419.2017.1366476. Epub 2017 Aug 20. PubMed PMID: 28823173.

19: Salunke M, Deshpande M, Bhalerao S. Experiential documentation of Trimad for its anti-obesity potential: A survey of Ayurvedic physicians from Pune city. J Ayurveda Integr Med. 2017 Jul - Sep;8(3):190-193. doi: 10.1016/j.jaim.2017.03.004. Epub 2017 Aug 16. PubMed PMID: 28822619; PubMed Central PMCID: PMC5607389.

20: Wu KC, Kao CP, Ho YL, Chang YS. Quality Control of the Root and Rhizome of Helminthostachys zeylanica (Daodi-Ugon) by HPLC Using Quercetin and Ugonins as Markers. Molecules. 2017 Jul 5;22(7). pii: E1115. doi: 10.3390/molecules22071115. PubMed PMID: 28678195.