Vinbarbital

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MedKoo CAT#: 581422

CAS#: 125-42-8

Description: Vinbarbital is discontinued (DEA controlled substance). It is a hypnotic drug which is a barbiturate derivative.


Price and Availability

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Pricing updated 2020-04-09. Prices are subject to change without notice.

Vinbarbital is discontinued (DEA controlled substance).


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 581422
Name: Vinbarbital
CAS#: 125-42-8
Chemical Formula: C11H16N2O3
Exact Mass: 224.1161
Molecular Weight: 224.26
Elemental Analysis: C, 58.91; H, 7.19; N, 12.49; O, 21.40


Synonym: Vinbarbital; Butenemalum; Butenemal; Delvinal; Vinbarbitalum

IUPAC/Chemical Name: 5-Ethyl-5-(1-methyl-1-butenyl)barbiturate

InChi Key: RAFOHKSPUDGZPR-VOTSOKGWSA-N

InChi Code: InChI=1S/C11H16N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h6H,4-5H2,1-3H3,(H2,12,13,14,15,16)/b7-6+

SMILES Code: O=C(NC(C1(CC)/C(C)=C/CC)=O)NC1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Maurer HH. Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass spectrometry. J Chromatogr. 1990 Sep 14;530(2):307-26. PubMed PMID: 2079506.

2: Poklis A, Hameli AZ. Two unusual barbiturate deaths. Arch Toxicol. 1975 Sep 5;34(1):77-80. PubMed PMID: 1242639.

3: Boucher M, Jallade S, Gorrée S. [Clinical trial of Sonuctane (vinbarbital) in neuropsychiatric patients. (50 cases)]. Rev Lyon Med. 1969 Apr 15;18(7):257-65. French. PubMed PMID: 5363794.

4: Cathelin M, Hosxe G. [Study of vinbarbital in stomatology]. Therapeutique. 1969 Apr;45(4):399-401. French. PubMed PMID: 5386072.

5: Warembourg H, Delbecque H. [Clinical study of Sonuctane (Vinbarbital) with 40 cardiac cases]. Lille Med. 1968 Dec;13(10):Suppl 7:1050+. French. PubMed PMID: 5720289.

6: Reber LA, Pathamanon C. The solubility of vinbarbital in ethanol-water systems. Am J Pharm Sci Support Public Health. 1967 Nov-Dec;139(6):234-8. PubMed PMID: 5630396.

7: HOFFNAGLE GF, MILLIGAN ML. Assay of aminophylline-vinbarbital solutions. J Am Pharm Assoc Am Pharm Assoc. 1952 Jan;41(1):3-5. PubMed PMID: 14907481.

8: HUGHES JG, HILL FS, GREEN CR, DAVIS BC. Electroencephalography of the newborn. V. Brain potentials of babies born of mothers given meperidine hydrochloride (demerol hydrochloride), vinbarbital sodium (delvinal sodium) or morphine. Am J Dis Child. 1950 Jun;79(6):998-1007. PubMed PMID: 15425471.

9: MUELLER VA. An analysis and evaluation of vinbarbital sodium for obstetric amnesia and analgesia. Am J Obstet Gynecol. 1950 Mar;59(3):679-84. PubMed PMID: 15405833.

10: WEBB CR. A report on the use of vinbarbital sodium in obstetrics. Memphis Med J. 1949 Sep;24(9):158. PubMed PMID: 18140745.

11: FOURNIER LG. The clinical use of sodium vinbarbital by the intravenous route in obstetrics. Am J Obstet Gynecol. 1948 Nov;56(5):913-20. PubMed PMID: 18888224.

12: BURWELL JC Jr. Observations on the use of vinbarbital sodium in obstetrics. N C Med J. 1948 Oct;9(10):525-7. PubMed PMID: 18888884.

13: KOHL MF. Intravenous vinbarbital sodium for obstetric analgesia. Am J Obstet Gynecol. 1948 Oct;56(4):811-4. PubMed PMID: 18882845.

14: LEWIS MS, BODDIE JB Jr. Vinbarbital sodium for obstetric amnesia, analgesia and anesthesia; a report of 3,000 cases. South Med J. 1948 Sep;41(9):820-9. PubMed PMID: 18879672.

15: BURKONS HF. Rapid obstetric analgesia by means of intravenous vinbarbital sodium. Am J Obstet Gynecol. 1948 Sep;56(3):549-52. PubMed PMID: 18877189.

16: LEWIS MS. Vinbarbital sodium for obstetric amnesia, analgesia, and anesthesia. Am J Obstet Gynecol. 1946 Mar;51:395-402. PubMed PMID: 21017075.

17: DAVIDSON NR. The use of sodium vinbarbital in obstetrics. South Med J. 1945 Dec;38:790-3. PubMed PMID: 21004153.