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MedKoo CAT#: 584584

CAS#: 1268709-57-4

Description: C3 is a selective microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 380 2 Weeks
50mg USD 1110 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-12. Prices are subject to change without notice.

C3, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 584584
Name: C3
CAS#: 1268709-57-4
Chemical Formula: C23H34N4O
Exact Mass: 382.2733
Molecular Weight: 382.552
Elemental Analysis: C, 72.21; H, 8.96; N, 14.65; O, 4.18

Synonym: C3

IUPAC/Chemical Name: N-Cyclopentyl-1-[5,6-dimethyl-1-(1-methylethyl)-1H-benzimidazol-2-yl]-4-piperidinecarboxamide


InChi Code: InChI=1S/C23H34N4O/c1-15(2)27-21-14-17(4)16(3)13-20(21)25-23(27)26-11-9-18(10-12-26)22(28)24-19-7-5-6-8-19/h13-15,18-19H,5-12H2,1-4H3,(H,24,28)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


Leclerc et al (2013) Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. Prostaglandins Other Lipid Mediat. 107 26 PMID: 24045148

Ozen et al (2017) Inhibition of microsomal PGE synthase-1 reduces human vascular tone by increasing PGI2: a safer alternative to COX-2 inhibition. Br.J.Pharmacol. 174 4087 PMID: 28675448

Olesch et al (2015) MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer. Oncotarget 6 10284 PMID: 25871398