WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 564058
Description: ZX-J-19L is an inhibitor of Cyclophilin J (CyPJ) PPIase. ZX-J-19L demonstrates remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil.
MedKoo Cat#: 564058
Chemical Formula: C24H21N3O
Exact Mass: 367.1685
Molecular Weight: 367.45
Elemental Analysis: C, 78.45; H, 5.76; N, 11.44; O, 4.35
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: ZX-J-19L; ZXJ19L; ZX J 19L; ZXJ-19L; ZX J-19L
IUPAC/Chemical Name: N-(2,3-Diphenylquinoxalin-6-yl)butyramide
InChi Key: ACDUESKKNRCKDL-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H21N3O/c1-2-9-22(28)25-19-14-15-20-21(16-19)27-24(18-12-7-4-8-13-18)23(26-20)17-10-5-3-6-11-17/h3-8,10-16H,2,9H2,1H3,(H,25,28)
SMILES Code: CCCC(NC1=CC=C2N=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=NC2=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 367.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Zhao X, Xia C, Wang X, Wang H, Xin M, Yu L, Liang Y. Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity. Front Pharmacol. 2018 Feb 21;9:126. doi: 10.3389/fphar.2018.00126. eCollection 2018. PubMed PMID: 29520233; PubMed Central PMCID: PMC5826973.