1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572901

CAS#: 146474-00-2

Description: 1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt is a PEG Linker.


Price and Availability

Size
Price

250mg
USD 330
Size
Price

500mg
USD 500
Size
Price

1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 572901
Name: 1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt
CAS#: 146474-00-2
Chemical Formula: C6H8N2O2
Exact Mass: 140.0586
Molecular Weight: 140.14
Elemental Analysis: C, 51.42; H, 5.75; N, 19.99; O, 22.83


Synonym: 1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt

IUPAC/Chemical Name: 1-(2-aminoethyl)-1H-pyrrole-2,5-dione

InChi Key: ODVRLSOMTXGTMX-UHFFFAOYSA-N

InChi Code: InChI=1S/C6H8N2O2/c7-3-4-8-5(9)1-2-6(8)10/h1-2H,3-4,7H2

SMILES Code: NCCN1C(C=CC1=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550.

2: Harrison E, Coulter JA, Dixon D. Gold nanoparticle surface functionalization: mixed monolayer versus hetero bifunctional peg linker. Nanomedicine (Lond). 2016 Apr;11(7):851-65. Review. PubMed PMID: 27021417.

3: Augusto MT, Hollmann A, Porotto M, Moscona A, Santos NC. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length. Molecules. 2017 Jul 15;22(7). pii: E1190. doi: 10.3390/molecules22071190. PubMed PMID: 28714870; PubMed Central PMCID: PMC5776016.

4: Tuma R, Russell M, Rosendahl M, Thomas GJ Jr. Solution conformation of the extracellular domain of the human tumor necrosis factor receptor probed by Raman and UV-resonance Raman spectroscopy: structural effects of an engineered PEG linker. Biochemistry. 1995 Nov 21;34(46):15150-6. PubMed PMID: 7578129.

5: Kanazaki K, Sano K, Makino A, Yamauchi F, Takahashi A, Homma T, Ono M, Saji H. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. doi:10.1016/j.jconrel.2016.02.017. Epub 2016 Feb 8. PubMed PMID: 26869546.