Jedi2
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MedKoo CAT#: 584545

CAS#: 651005-90-2

Description: Jedi2 is a Piezo1 channel activator that promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels and elicits responses in mouse Piezo1-transfected, but not Piezo2-transfected cells.


Chemical Structure

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Jedi2
CAS# 651005-90-2

Theoretical Analysis

MedKoo Cat#: 584545
Name: Jedi2
CAS#: 651005-90-2
Chemical Formula: C10H8O3S
Exact Mass: 208.0194
Molecular Weight: 208.231
Elemental Analysis: C, 57.68; H, 3.87; O, 23.05; S, 15.40

Price and Availability

Size Price Availability Quantity
10.0mg USD 210.0 2 Weeks
50.0mg USD 840.0 2 Weeks
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Synonym: Jedi2

IUPAC/Chemical Name: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid

InChi Key: YXDCRSXNEOKXDE-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)

SMILES Code: O=C(C1=C(C)OC(C2=CC=CS2)=C1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 208.231 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Wang et al (2018) A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel. Nat.Commun. 9 1300 PMID: 29610524

Jedi2

10.0mg / USD 210.0