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MedKoo CAT#: 563840

CAS#: 1295505-76-8

Description: BAY-438 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-12. Prices are subject to change without notice.

BAY-438 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 563840
Name: BAY-438
CAS#: 1295505-76-8
Chemical Formula: C20H16F3IN4O4S
Exact Mass: 591.9889
Molecular Weight: 592.33
Elemental Analysis: C, 40.55; H, 2.72; F, 9.62; I, 21.42; N, 9.46; O, 10.80; S, 5.41

Synonym: BAY-438; BAY438; BAY 438

IUPAC/Chemical Name: 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-(3-((sulfamoylamino)methyl)phenoxy)benzamide


InChi Code: InChI=1S/C20H16F3IN4O4S/c21-13-7-11(24)4-5-15(13)28-19-17(20(25)29)16(8-14(22)18(19)23)32-12-3-1-2-10(6-12)9-27-33(26,30)31/h1-8,27-28H,9H2,(H2,25,29)(H2,26,30,31)

SMILES Code: O=C(N)C1=C(OC2=CC=CC(CNS(=O)(N)=O)=C2)C=C(F)C(F)=C1NC3=CC=C(I)C=C3F

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: