GeA-69
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563775

CAS#: 2143475-98-1

Description: GeA-69 is a novel selective allosteric inhibitor targeting macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14.


Price and Availability

Size
Price

1g
USD 3950
Size
Price

2g
USD 7650
Size
Price

GeA-69, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 563775
Name: GeA-69
CAS#: 2143475-98-1
Chemical Formula: C20H16N2O
Exact Mass: 300.1263
Molecular Weight: 300.36
Elemental Analysis: C, 79.98; H, 5.37; N, 9.33; O, 5.33


Synonym: GeA-69; GeA69; GeA 69

IUPAC/Chemical Name: N-(2-(9H-carbazol-1-yl)phenyl)acetamide

InChi Key: LDPDVNYCIOHPGF-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H16N2O/c1-13(23)21-18-11-4-2-7-14(18)16-9-6-10-17-15-8-3-5-12-19(15)22-20(16)17/h2-12,22H,1H3,(H,21,23)

SMILES Code: CC(NC1=CC=CC=C1C2=CC=CC3=C2NC4=C3C=CC=C4)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Schuller M, Riedel K, Gibbs-Seymour I, Uth K, Sieg C, Gehring AP, Ahel I, Bracher F, Kessler BM, Elkins JM, Knapp S. Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. ACS Chem Biol. 2017 Nov 17;12(11):2866-2874. doi: 10.1021/acschembio.7b00445. Epub 2017 Oct 19. PubMed PMID: 28991428; PubMed Central PMCID: PMC6089342.