1,1,1-Trifluoroethyl-PEG5-alcohol
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572520

CAS#: 1807512-41-9

Description: 1,1,1-Trifluoroethyl-PEG5-alcohol is a PEG Linker.


Price and Availability

Size
Price

250mg
USD 530
Size
Price

500mg
USD 830
Size
Price

1g
USD 1300

1,1,1-Trifluoroethyl-PEG5-alcohol, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 572520
Name: 1,1,1-Trifluoroethyl-PEG5-alcohol
CAS#: 1807512-41-9
Chemical Formula: C10H19F3O5
Exact Mass: 276.1185
Molecular Weight: 276.25
Elemental Analysis: C, 43.48; H, 6.93; F, 20.63; O, 28.96


Synonym: 1,1,1-Trifluoroethyl-PEG5-alcohol

IUPAC/Chemical Name: 14,14,14-trifluoro-3,6,9,12-tetraoxatetradecan-1-ol

InChi Key: WRLCZARSFIXUQS-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H19F3O5/c11-10(12,13)9-18-8-7-17-6-5-16-4-3-15-2-1-14/h14H,1-9H2

SMILES Code: OCCOCCOCCOCCOCC(F)(F)F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151.

2: Saifer MG, Williams LD, Sobczyk MA, Michaels SJ, Sherman MR. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46. doi: 10.1016/j.molimm.2013.07.014. Epub 2013 Nov 5. PubMed PMID: 24200843.

3: Garay RP, El-Gewely R, Armstrong JK, Garratty G, Richette P. Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents. Expert Opin Drug Deliv. 2012 Nov;9(11):1319-23. doi: 10.1517/17425247.2012.720969. Epub 2012 Aug 30. PubMed PMID: 22931049.