BDP FL-PEG4-TCO
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572361

CAS#: 2183473-16-5

Description: BDP FL-PEG4-TCO is a fluorescent PEG derivative. PEG Linkers and derivatives may be useful in the development of antibody drug conjugates.


Price and Availability

Size
Price

5mg
USD 460
Size
Price

10mg
USD 740
Size
Price

25mg
USD 1130

BDP FL-PEG4-TCO, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 572361
Name: BDP FL-PEG4-TCO
CAS#: 2183473-16-5
Chemical Formula: C33H49BF2N4O7
Exact Mass: 662.3662
Molecular Weight: 662.58
Elemental Analysis: C, 59.82; H, 7.45; B, 1.63; F, 5.73; N, 8.46; O, 16.90


Synonym: BDP FL-PEG4-TCO

IUPAC/Chemical Name: (E)-cyclooct-4-en-1-yl (18-(5,5-difluoro-7,9-dimethyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-16-oxo-3,6,9,12-tetraoxa-15-azaoctadecyl)carbamate

InChi Key: FISJDIFFUFNJNS-ONEGZZNKSA-N

InChi Code: InChI=1S/C33H49BF2N4O7/c1-26-24-27(2)39-31(26)25-29-11-10-28(40(29)34(39,35)36)12-13-32(41)37-14-16-43-18-20-45-22-23-46-21-19-44-17-15-38-33(42)47-30-8-6-4-3-5-7-9-30/h3-4,10-11,24-25,30H,5-9,12-23H2,1-2H3,(H,37,41)(H,38,42)/b4-3+

SMILES Code: F[B-]1(F)[N+]2=C(C)C=C(C)C2=CC3=CC=C(CCC(NCCOCCOCCOCCOCCNC(OC4CC/C=C/CCC4)=O)=O)N13


Technical Data

Appearance:
Solid powder

Purity:
>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, DMF, DCM

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


Additional Information

Solubility: DMSO, DMF, DCM, low solubility in water
Excitation maximum (nm): 503
Extinction coefficient and excitation maximum, Lmol-1cm-1: 80000
Emission maximum (nm): 509
Fluorescence quantum yield: 0.9


References

1: Chen X, Zhang X, Wang HY, Chen Z, Wu FG. Subcellular Fate of a Fluorescent Cholesterol-Poly(ethylene glycol) Conjugate: An Excellent Plasma Membrane Imaging Reagent. Langmuir. 2016 Oct 4;32(39):10126-10135. Epub 2016 Sep 21. PubMed PMID: 27597442.

2: Chen G, Wang L, Cordie T, Vokoun C, Eliceiri KW, Gong S. Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging. Biomaterials. 2015 Apr;47:41-50. doi: 10.1016/j.biomaterials.2015.01.006. Epub 2015 Feb 4. PubMed PMID: 25682159; PubMed Central PMCID: PMC4329508.

3: Ruan S, Qian J, Shen S, Chen J, Zhu J, Jiang X, He Q, Yang W, Gao H. Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration. Bioconjug Chem. 2014 Dec 17;25(12):2252-9. doi: 10.1021/bc500474p. Epub 2014 Nov 11. PubMed PMID: 25387274.

4: Ruan S, Wan J, Fu Y, Han K, Li X, Chen J, Zhang Q, Shen S, He Q, Gao H. PEGylated fluorescent carbon nanoparticles for noninvasive heart imaging. Bioconjug Chem. 2014 Jun 18;25(6):1061-8. doi: 10.1021/bc5001627. Epub 2014 May 22. PubMed PMID: 24852402.

5: Paira TK, Saha A, Banerjee S, Das T, Das P, Jana NR, Mandal TK. Fluorescent amphiphilic PEG-peptide-PEG triblock conjugate micelles for cell imaging. Macromol Biosci. 2014 Jul;14(7):929-35. doi: 10.1002/mabi.201400083. Epub 2014 Mar 31. PubMed PMID: 24687698.

6: Okuda T, Kobayashi Y, Yanamoto S, Okamoto H. PEG conjugation of a near-infrared fluorescent probe for noninvasive dual imaging of lung deposition and gene expression by pulmonary gene delivery. J Drug Target. 2012 Nov;20(9):801-12. doi: 10.3109/1061186X.2012.722639. Epub 2012 Sep 26. PubMed PMID: 23009266.