L-739758

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563674

CAS#: 168157-33-3

Description: L-739758 is a glycoprotein IIb/IIIa inhibitor.


Price and Availability

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Price

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L-739758 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563674
Name: L-739758
CAS#: 168157-33-3
Chemical Formula: C22H26N4O5S3
Exact Mass: 522.1065
Molecular Weight: 522.65
Elemental Analysis: C, 50.56; H, 5.01; N, 10.72; O, 15.31; S, 18.40


Synonym: L-739758; L 739758; L739758;

IUPAC/Chemical Name: (2S)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]-2-(pyridin-3-ylsulfonylamino)propanoic acid

InChi Key: QDIFCBMBPLLNGR-SFHVURJKSA-N

InChi Code: InChI=1S/C22H26N4O5S3/c27-20(25-13-18(21(28)29)26-34(30,31)17-2-1-7-24-12-17)19-11-15-10-16(32-22(15)33-19)4-3-14-5-8-23-9-6-14/h1-2,7,10-12,14,18,23,26H,3-6,8-9,13H2,(H,25,27)(H,28,29)/t18-/m0/s1

SMILES Code: O=C(O)[C@@H](NS(=O)(C1=CC=CN=C1)=O)CNC(C(S2)=CC3=C2SC(CCC4CCNCC4)=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Shen YT, Wiedmann RT, Lynch JJ Jr, Gould RJ. Platelet glycoprotein IIb/IIIa receptor inhibitor preserves coronary flow reserve during progressive coronary arteriostenosis in swine. Arterioscler Thromb Vasc Biol. 2000 Oct;20(10):2309-15. PubMed PMID: 11031220.

2: Bednar B, Cook JJ, Holahan MA, Cunningham ME, Jumes PA, Bednar RA, Hartman GD, Gould RJ. Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa. Blood. 1999 Jul 15;94(2):587-99. PubMed PMID: 10397726.