SA 2572

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461680

CAS#: 112946-90-4

Description: SA 2572 is a newly synthesized Ca2+ antagonist having a inhibitory effect on the fast Na+ inward channel.


Chemical Structure

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SA 2572
CAS# 112946-90-4

Theoretical Analysis

MedKoo Cat#: 461680
Name: SA 2572
CAS#: 112946-90-4
Chemical Formula: C32H41ClN2O6S
Exact Mass: 616.24
Molecular Weight: 617.190
Elemental Analysis: C, 62.27; H, 6.70; Cl, 5.74; N, 4.54; O, 15.55; S, 5.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: SA 2572; SA-2572; SA2572;

IUPAC/Chemical Name: 1-(2-(5-methoxy-2-(4-(methyl(3,4,5-trimethoxyphenethyl)amino)butoxy)phenyl)benzo[d]thiazol-3(2H)-yl)ethan-1-one hydrochloride

InChi Key: AONMOOKWGFXUKH-UHFFFAOYSA-N

InChi Code: InChI=1S/C32H40N2O6S.ClH/c1-22(35)34-26-11-7-8-12-30(26)41-32(34)25-21-24(36-3)13-14-27(25)40-18-10-9-16-33(2)17-15-23-19-28(37-4)31(39-6)29(20-23)38-5;/h7-8,11-14,19-21,32H,9-10,15-18H2,1-6H3;1H

SMILES Code: COC1=C(OC)C(OC)=CC(CCN(CCCCOC2=CC=C(OC)C=C2C3SC4=CC=CC=C4N3C(C)=O)C)=C1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 617.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Miyawaki N, Furuta T, Shigei T. Electrophysiologic effects of a novel Ca antagonist, SA2572, in isolated rabbit and guinea pig hearts. J Cardiovasc Pharmacol. 1988 Jul;12(1):65-71. PubMed PMID: 2459537.

2: Fujita M, Ota A, Ito S, Yamamoto K, Kawashima Y, Iso T, Iwao J. Synthesis and calcium antagonistic activity of (+)-(R)- and (-)-(S)-3-acetyl-2-[5-methoxy-2-[4-[N-methyl-N-(3,4,5- trimethoxyphenethyl)amino]butoxy]phenyl]benzothiazoline hydrochloride. Chem Pharm Bull (Tokyo). 1990 Apr;38(4):936-41. PubMed PMID: 2379287.