DC-S239
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563641

CAS#: 303141-21-1

Description: DC-S239 is a potent and selective histone methyltransferase SET7 inhibitor.

Chemical Structure

img
DC-S239
CAS# 303141-21-1
Instruction

Theoretical Analysis

MedKoo Cat#: 563641
Name: DC-S239
CAS#: 303141-21-1
Chemical Formula: C15H15N3O5S
Exact Mass: 349.07
Molecular Weight: 349.360
Elemental Analysis: C, 51.57; H, 4.33; N, 12.03; O, 22.90; S, 9.18

Price and Availability

Size Price Availability Quantity
25mg USD 750 2 Weeks
50mg USD 1250 2 Weeks
100mg USD 2050 2 Weeks
Bulk inquiry

Related CAS #: 303141-21-1,  

Synonym: DC-S239; DC S239; DCS239;

IUPAC/Chemical Name: Ethyl 2-Amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate

InChi Key: SIVTXLSKYVOFHS-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H15N3O5S/c1-3-23-15(20)11-8(2)12(24-13(11)16)14(19)17-9-5-4-6-10(7-9)18(21)22/h4-7H,3,16H2,1-2H3,(H,17,19)

SMILES Code: O=C(C1=C(N)SC(C(NC2=CC=CC([N+]([O-])=O)=C2)=O)=C1C)OCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 349.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Ding H, Lu WC, Hu JC, Liu YC, Zhang CH, Lian FL, Zhang NX, Meng FW, Luo C, Chen KX. Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search. Molecules. 2018 Mar 2;23(3). pii: E567. doi: 10.3390/molecules23030567. PubMed PMID: 29498708.

2: Meng F, Cheng S, Ding H, Liu S, Liu Y, Zhu K, Chen S, Lu J, Xie Y, Li L, Liu R, Shi Z, Zhou Y, Liu YC, Zheng M, Jiang H, Lu W, Liu H, Luo C. Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening. J Med Chem. 2015 Oct 22;58(20):8166-81. doi: 10.1021/acs.jmedchem.5b01154. Epub 2015 Sep 30. PubMed PMID: 26390175.