Veronicastroside

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 599191

CAS#: 25694-72-8

Description: Veronicastroside is a flavonoid.


Price and Availability

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Veronicastroside is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 599191
Name: Veronicastroside
CAS#: 25694-72-8
Chemical Formula: C27H30O15
Exact Mass: 594.1585
Molecular Weight: 594.52
Elemental Analysis: C, 54.55; H, 5.09; O, 40.37


Synonym: Veronicastroside; Lonicerin; Scolymoside;

IUPAC/Chemical Name: 7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-chromen-4-one

InChi Key: SHPPXMGVUDNKLV-KMFFXDMSSA-N

InChi Code: InChI=1S/C27H30O15/c1-9-20(33)22(35)24(37)26(38-9)42-25-23(36)21(34)18(8-28)41-27(25)39-11-5-14(31)19-15(32)7-16(40-17(19)6-11)10-2-3-12(29)13(30)4-10/h2-7,9,18,20-31,33-37H,8H2,1H3/t9-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1

SMILES Code: O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)=CC(O)=C13


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Inouye H, Aoki Y, Wagner H, Hörhammer L, Aurnhammer G, Budweg W. [The flavone glycosides from Veronicastrum sibiricum Pennell var. japonicum Hara and synthesis of luteolin-7-neohesperidoside (veronicastroside)]. Chem Ber. 1969;102(9):3009-13. German. PubMed PMID: 5806152.

2: Inagaki I, Sakushima A, Hisada S, Nishibe S, Morita N. [Comparison of lonicerin and veronicastroside (author's transl)]. Yakugaku Zasshi. 1974 Apr;94(4):524-5. Japanese. PubMed PMID: 4473018.

3: Lee JH, Han Y. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9. doi: 10.1007/s12272-011-0520-6. Epub 2011 Jun 9. PubMed PMID: 21656372.

4: Lin YP, Chen TY, Tseng HW, Lee MH, Chen ST. Neural cell protective compounds isolated from Phoenix hanceana var. formosana. Phytochemistry. 2009 Jun;70(9):1173-81. doi: 10.1016/j.phytochem.2009.06.006. Epub 2009 Jul 21. PubMed PMID: 19628235.

5: Kim NM, Kim J, Chung HY, Choi JS. Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana. Arch Pharm Res. 2000 Jun;23(3):237-9. PubMed PMID: 10896054.

6: Hammouda FM, Seif el-Nasr MM, Shahat AA. Flavonoids of Cynara scolymus L. cultivated in Egypt. Plant Foods Hum Nutr. 1993 Sep;44(2):163-9. PubMed PMID: 8378274.

7: Huang X, Li SL, Li P, Li HJ, Chai XY, Song Y. Simultaneous determination of eight main flavonoids in Flos lonicerae by high performance liquid chromatography. Yao Xue Xue Bao. 2005 Mar;40(3):285-8. PubMed PMID: 15952605.

8: Shen CY, Jiang JG, Huang CL, Zhu W, Zheng CY. Polyphenols from Blossoms of Citrus aurantium L. var. amara Engl. Show Significant Anti-Complement and Anti-Inflammatory Effects. J Agric Food Chem. 2017 Oct 18;65(41):9061-9068. doi: 10.1021/acs.jafc.7b03759. Epub 2017 Oct 9. PubMed PMID: 28942652.