Viquidil

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 599092

CAS#: 84-55-9

Description: Viquidil is a vasodilator agent.

Chemical Structure

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Viquidil
CAS# 84-55-9
Instruction

Theoretical Analysis

MedKoo Cat#: 599092
Name: Viquidil
CAS#: 84-55-9
Chemical Formula: C20H24N2O2
Exact Mass: 324.18
Molecular Weight: 324.420
Elemental Analysis: C, 74.05; H, 7.46; N, 8.63; O, 9.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Viquidil; LM 192; LM-192; LM-192; Viquidilum;

IUPAC/Chemical Name: 1-(6-methoxyquinolin-4-yl)-3-(3-vinylpiperidin-4-yl)propan-1-one

InChi Key: DKRSEIPLAZTSFD-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24N2O2/c1-3-14-13-21-10-8-15(14)4-7-20(23)17-9-11-22-19-6-5-16(24-2)12-18(17)19/h3,5-6,9,11-12,14-15,21H,1,4,7-8,10,13H2,2H3

SMILES Code: O=C(C1=CC=NC2=CC=C(OC)C=C12)CCC3C(C=C)CNCC3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 324.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Guérémy C, Uzan A, Tamen JC. [Viquidil: study of metabolism using the isotope method. I. Synthesis of 14C-labelled viquidil]. Arzneimittelforschung. 1972 Aug;22(8):1336-40. French. PubMed PMID: 4678396.

2: De Valois JC. Increase in cerebral blood flow in the rabbit by viquidil. Stroke. 1973 Mar-Apr;4(2):218-20. PubMed PMID: 4702310.

3: Hünermann B, Felix R, Wesener K, Winkler C. [Effect of Viquidil on cerebral circulation. Studies using a scintillation camera-computer system]. Arzneimittelforschung. 1973 Aug;23(8):1074-6. German. PubMed PMID: 4801028.

4: Boudouresques J, Gosset A. [Treatment of vascular diseases of the nervous system with Viquidil hydrochloride]. Mars Med. 1972;109(6):453-6. French. PubMed PMID: 4563604.

5: Uzan A, Guérémy C. [Viquidil: study of its metabolism by an isotopic method. 3. Excretion and biotransformation in animals]. Arzneimittelforschung. 1974 Jan;24(1):34-9. French. PubMed PMID: 4406106.

6: Uzan A, Guérémy C. [Viquidil: study of metabolism using the isotope method. II. Absorption and distribution of 14C-labelled viquidil in animals]. Arzneimittelforschung. 1972 Aug;22(8):1341-6. French. PubMed PMID: 4678397.

7: Sim AK, Uzan A. The antithrombotic activity of viquidil, a cerebral vasodilator. Arzneimittelforschung. 1979;29(3):508-11. PubMed PMID: 582736.

8: Cosnier D, Cheucle M, Rispat G, Streichenberger G. Influence of hypercapnia on the cerebrovascular activities of some drugs used in the treatment of cerebral ischemia. Arzneimittelforschung. 1977;27(8):1566-9. PubMed PMID: 578747.

9: Cargnelli G, Finotti P, Melacini P, Ferrari M. [Effects of viquidil on the electric and mechanical activity of smooth muscle]. Boll Soc Ital Biol Sper. 1976 Nov 15;52(21):1808-13. Italian. PubMed PMID: 1037429.

10: Lecrubier C, Uzan A, Samama M. [Effect of a new cerebral vasodilator agent, viquidil, on the aggregation of blood platelets]. Arzneimittelforschung. 1972 Aug;22(8):1334-6. French. PubMed PMID: 4678395.

11: N'Diaye IP, Girard PL, Dumas M. [Trial of a new cerebral vasoregulator: viquidil hydrochloride, in black Africans]. Bull Soc Med Afr Noire Lang Fr. 1974;19(3):257-9. French. PubMed PMID: 4457255.

12: Lebiediewa NW. [Current treatment of cerebrovascular disorder with vasoactive drugs]. Neurol Neurochir Pol. 1981 Jul-Aug;15(4):417-21. Polish. PubMed PMID: 6895779.

13: Nihard P. [Does fluororetinography permit evaluation of the action of drugs: myth or reality?]. Bull Soc Belge Ophtalmol. 1981;192:93-102. French. PubMed PMID: 6896665.

14: Nowicki JP, MacKenzie ET, Spinnewyn B. Effects of agents used in the pharmacotherapy of cerebrovascular disease on the oxygen consumption of isolated cerebral mitochondria. J Cereb Blood Flow Metab. 1982;2(1):33-40. PubMed PMID: 7061602.