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BDP FL DBCO
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 572271

CAS#: 2093197-94-3

Description: BDP FL DBCO is a PEG derivative containing a reactive DBCO group. DBCO will react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst.


Price and Availability

Size
Price
1mg
USD 370
Size
Price
2mg
USD 580
Size
Price
5mg
USD 990

BDP FL DBCO, purity > 95%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 572271
Name: BDP FL DBCO
CAS#: 2093197-94-3
Chemical Formula: C32H29BF2N4O2+
Exact Mass: 550.2346
Molecular Weight: 550.42
Elemental Analysis: C, 69.83; H, 5.31; B, 1.96; F, 6.90; N, 10.18; O, 5.81


Synonym: BDP FL DBCO

IUPAC/Chemical Name: BDP FL DBCO

InChi Key: WDIIYUOZPVBPFM-UHFFFAOYSA-N

InChi Code: InChI=1S/C32H29BF2N4O2/c1-22-19-23(2)38-30(22)20-28-14-13-27(39(28)33(38,34)35)15-16-31(40)36-18-17-32(41)37-21-26-9-4-3-7-24(26)11-12-25-8-5-6-10-29(25)37/h3-10,13-14,19-20H,15-18,21H2,1-2H3,(H,36,40)/q+1

SMILES Code: O=C(CCNC(CCC1=CC=C2N1B(F)(F)[N+]3=C(C)C=C(C)C3=C2)=O)N4CC5=C(C=CC=C5)C#CC6=C4C=CC=C6


Technical Data

Appearance:
Solid powder

Purity:
>95% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, DMF, DCM

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


Additional Information

Solubility: DMSO, DMF, DCM
Excitation maximum (nm): 504
Extinction coefficient and excitation maximum, Lmol-1cm-1: 85000
Emission maximum (nm): 514


References

1: Wang H, Tang L, Liu Y, Dobrucka IT, Dobrucki LW, Yin L, Cheng J. In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. Theranostics. 2016 Jun 16;6(9):1467-76. doi: 10.7150/thno.16003. eCollection 2016. PubMed PMID: 27375793; PubMed Central PMCID: PMC4924513.

2: Yoon HI, Yhee JY, Na JH, Lee S, Lee H, Kang SW, Chang H, Ryu JH, Lee S, Kwon IC, Cho YW, Kim K. Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo. Bioconjug Chem. 2016 Apr 20;27(4):927-36. doi: 10.1021/acs.bioconjchem.6b00010. Epub 2016 Mar 10. PubMed PMID: 26930274.

3: Zimmerman ES, Heibeck TH, Gill A, Li X, Murray CJ, Madlansacay MR, Tran C, Uter NT, Yin G, Rivers PJ, Yam AY, Wang WD, Steiner AR, Bajad SU, Penta K, Yang W, Hallam TJ, Thanos CD, Sato AK. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61. doi: 10.1021/bc400490z. Epub 2014 Jan 29. PubMed PMID: 24437342.