WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563569
Description: BAY32-5915 is an IKKalpha inhibitor.
MedKoo Cat#: 563569
Chemical Formula: C10H7NO3
Exact Mass: 189.0426
Molecular Weight: 189.17
Elemental Analysis: C, 63.49; H, 3.73; N, 7.40; O, 25.37
Synonym: BAY32-5915; BAY32 5915; BAY325915; BAY 32 5915; BAY-32-5915; BAY 32-5915;
IUPAC/Chemical Name: 8-Hydroxyquinoline-2-carboxylic acid
InChi Key: UHBIKXOBLZWFKM-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)
SMILES Code: O=C(C1=NC2=C(O)C=CC=C2C=C1)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 189.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pletz N, Schön M, Ziegelbauer K, Emmert S, Liu N, Dobbelstein M, Schön MP. Doxorubicin-induced activation of NF-κB in melanoma cells is abrogated by inhibition of IKKβ, but not by a novel IKKα inhibitor. Exp Dermatol. 2012 Apr;21(4):301-4. doi: 10.1111/j.1600-0625.2012.01440.x. Epub 2012 Feb 10. PubMed PMID: 22320445.