BX-513 HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563566

CAS#: 193542-65-3

Description: BX-513 HCl is a selective CCR1 receptor antagonist.


Price and Availability

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BX-513 HCl is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563566
Name: BX-513 HCl
CAS#: 193542-65-3
Chemical Formula: C28H30Cl2N2O
Exact Mass: 480.1735
Molecular Weight: 481.46
Elemental Analysis: C, 69.85; H, 6.28; Cl, 14.73; N, 5.82; O, 3.32


Synonym: BX-513 hydrochloride; BX-513 HCl; BX 513 HCl; BX513 HCl; BX 513 hydrochloride; BX513 hydrochloride; VUF 2274; VUF-2274; VUF2274;

IUPAC/Chemical Name: 5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile hydrochloride

InChi Key: SSZWNUGWOGONQJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H29ClN2O.ClH/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24;/h1-6,8-15,32H,7,16-21H2;1H

SMILES Code: N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Di Prisco S, Merega E, Pittaluga A. Functional adaptation of presynaptic chemokine receptors in EAE mouse central nervous system. Synapse. 2014 Nov;68(11):529-35. doi: 10.1002/syn.21774. Epub 2014 Aug 19. PubMed PMID: 25092801.

2: Di Prisco S, Summa M, Chellakudam V, Rossi PI, Pittaluga A. RANTES-mediated control of excitatory amino acid release in mouse spinal cord. J Neurochem. 2012 May;121(3):428-37. doi: 10.1111/j.1471-4159.2012.07720.x. Epub 2012 Mar 21. PubMed PMID: 22385043.