Virustomycin A
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MedKoo CAT#: 592749

CAS#: 84777-85-5

Description: Virustomycin A is a macrolide antibiotic active against infectious and plant pathogenic fungi. It decreases plaque formation by RNA and DNA viruses.


Price and Availability

Size Price Shipping out time Quantity
1mg USD 280 2 Weeks
5mg USD 935 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-10. Prices are subject to change without notice.

Virustomycin A, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 592749
Name: Virustomycin A
CAS#: 84777-85-5
Chemical Formula: C48H71NO14
Exact Mass: 885.4875
Molecular Weight: 886.089
Elemental Analysis: C, 65.06; H, 8.08; N, 1.58; O, 25.28


Synonym: Virustomycin A; Antibiotic AM-2604 A

IUPAC/Chemical Name: Concanamycin A, 23-O-de(4-O-(aminocarbonyl)-2,6-dideoxy-beta-D-arabino-hexopyranosyl)-23-O-(4-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-1,4-dioxo-2-butenyl)-

InChi Key: YIKWIQAIKGWYCF-QTAFVZCYSA-N

InChi Code: InChI=1S/C48H71NO14/c1-12-15-36-30(7)39(61-41(53)21-20-40(52)49-42-34(50)18-19-35(42)51)25-48(58,63-36)32(9)45(56)31(8)46-37(59-10)17-14-16-26(3)22-28(5)43(54)33(13-2)44(55)29(6)23-27(4)24-38(60-11)47(57)62-46/h12,14-17,20-21,23-24,28-33,36-37,39,43-46,50,54-56,58H,13,18-19,22,25H2,1-11H3,(H,49,52)/b15-12-,17-14+,21-20+,26-16+,27-23-,38-24-/t28-,29-,30-,31+,32+,33+,36-,37+,39-,43+,44-,45-,46+,48-/m1/s1

SMILES Code: C(\C=C\C(=O)NC1=C(CCC1=O)O)(=O)O[C@@H]1C[C@](O[C@@H]([C@H]1C)\C=C/C)(O)[C@H]([C@@H]([C@H](C)[C@@H]1OC(C(=CC(=C[C@H]([C@H]([C@H]([C@H]([C@@H](CC(=CC=C[C@@H]1OC)C)C)O)CC)O)C)C)OC)=O)O)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Otoguro K, Ishiyama A, Namatame M, Nishihara A, Furusawa T, Masuma R, Shiomi K, Takahashi Y, Yamada H, Omura S. Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites. J Antibiot (Tokyo). 2008 Jun;61(6):372-8. doi: 10.1038/ja.2008.52. PubMed PMID: 18667785.

2: Hayakawa Y, Takaku K, Furihata K, Nagai K, Seto H. Isolation and structural elucidation of new 18-membered macrolide antibiotics, viranamycins A and B. J Antibiot (Tokyo). 1991 Dec;44(12):1294-9. PubMed PMID: 1778781.

3: Omura S, Imamura N, Hinotozawa K, Otoguro K, Lukacs G, Faghih R, Tolmann R, Arison BH, Smith JL. The structure of virustomycin A. J Antibiot (Tokyo). 1983 Dec;36(12):1783-6. PubMed PMID: 6662820.

4: Omura S, Otoguro K, Tanaka H. The mode of action of a novel 18-membered macrolide, virustomycin A (AM-2604 A), on Trichomonas foetus. J Antibiot (Tokyo). 1983 Dec;36(12):1755-61. PubMed PMID: 6662816.

5: Omura S, Shimizu H, Iwai Y, Hinotozawa K, Otoguro K, Hashimoto H, Nakagawa A. AM-2604 A, a new antiviral antibiotic produced by a strain of Streptomyces. J Antibiot (Tokyo). 1982 Dec;35(12):1632-7. PubMed PMID: 7166528.