WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563532
Description: WWL123 is a novel α/ß-hydrolase domain 6 (ABHD6) inhibitor.
MedKoo Cat#: 563532
Chemical Formula: C28H24N2O3
Exact Mass: 436.1787
Molecular Weight: 436.51
Elemental Analysis: C, 77.04; H, 5.54; N, 6.42; O, 11.00
Synonym: WWL123; WWL-123; WWL 123;
IUPAC/Chemical Name: 4'-carbamoyl-[1,1'-biphenyl]-4-yl ([1,1'-biphenyl]-3-ylmethyl)(methyl)carbamate
InChi Key: UUJGYRHAOHORFC-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H24N2O3/c1-30(19-20-6-5-9-25(18-20)21-7-3-2-4-8-21)28(32)33-26-16-14-23(15-17-26)22-10-12-24(13-11-22)27(29)31/h2-18H,19H2,1H3,(H2,29,31)
SMILES Code: O=C(OC1=CC=C(C2=CC=C(C(N)=O)C=C2)C=C1)N(CC3=CC(C4=CC=CC=C4)=CC=C3)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 436.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Zhong P, Pan B, Gao XP, Blankman JL, Cravatt BF, Liu QS. Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. J Physiol. 2011 Oct 15;589(Pt 20):4847-55. doi: 10.1113/jphysiol.2011.215509. Epub 2011 Sep 12. PubMed PMID: 21911610; PubMed Central PMCID: PMC3224879.