WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592687

CAS#: 528-71-2

Description: Hemipyocyanine is the virulence factor of Pseudomonas aeruginosa.

Chemical Structure

CAS# 528-71-2

Theoretical Analysis

MedKoo Cat#: 592687
Name: Hemipyocyanine
CAS#: 528-71-2
Chemical Formula: C12H8N2O
Exact Mass: 196.0637
Molecular Weight: 196.209
Elemental Analysis: C, 73.46; H, 4.11; N, 14.28; O, 8.15

Price and Availability

Size Price Availability Quantity
25.0mg USD 215.0 2 Weeks
50.0mg USD 350.0 2 Weeks
100.0mg USD 535.0 2 Weeks
250.0mg USD 750.0 2 Weeks
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Synonym: Hemipyocyanine, NSC 88882

IUPAC/Chemical Name: 1-Phenazinol


InChi Code: InChI=1S/C12H8N2O/c15-11-7-3-6-10-12(11)14-9-5-2-1-4-8(9)13-10/h1-7,15H


Appearance: A crystalline solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 196.209 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Ramafi, G., Anderson, R., Theron, A., et al. Exposure of N-formyl-L-methionyl-L-leucyl-L-phenylalanine-activated human neutrophils to the Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine is associated with impaired calcium efflux and potentiation of primary granule enzyme release. Infect. Immun. 67(10), 5157-5162 (1999).

2. Sinha, S., Shen, X., Gallazzi, F., et al. Generation of reactive oxygen species mediated by 1‑hydroxyphenazine, a virulence factor of Pseudomonas aeruginosa. Chem. Res. Toxicol. 28(2), 175-181 (2015).

3. Munro, N.C., Barker, A., Rutman, A., et al. Effect of pyocyanin and 1-hydroxyphenazine on in vivo tracheal mucus velocity. J. Appl. Physiol. 67(1), 316-323 (1985).

4. Luo, Q., Hu, H., Peng, H., et al. Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510. Chin. J. Chem. Eng. 23(4), 699-703 (2015).