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MedKoo CAT#: 563502

CAS#: 39674-97-0

Description: BVT948 is a protein tyrosine phosphatases (PTP) inhibitor.

Price and Availability

Size Price Shipping out time Quantity
1mg USD 210 2 Weeks
5mg USD 350 2 Weeks
10mg USD 340 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-27. Prices are subject to change without notice.

BVT948, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 563502
Name: BVT948
CAS#: 39674-97-0
Chemical Formula: C14H11NO3
Exact Mass: 241.0739
Molecular Weight: 241.24
Elemental Analysis: C, 69.70; H, 4.60; N, 5.81; O, 19.90

Synonym: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3;

IUPAC/Chemical Name: 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione


InChi Code: InChI=1S/C14H11NO3/c1-14(2)9-10(15-13(14)18)7-5-3-4-6-8(7)11(16)12(9)17/h3-6,17H,1-2H3

SMILES Code: O=C(C(C)(C)C1=C2O)N=C1C3=CC=CC=C3C2=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Chen W, Ennes HS, McRoberts JA, Marvizón JC. Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced substance P release in the rat spinal cord. Neuropharmacology. 2018 Jan;128:255-268. doi: 10.1016/j.neuropharm.2017.10.014. Epub 2017 Oct 16. PubMed PMID: 29042318; PubMed Central PMCID: PMC5726399.

2: Mironova GY, Avdonin PP, Goncharov NV, Jenkins RO, Avdonin PV. Inhibition of protein tyrosine phosphatases unmasks vasoconstriction and potentiates calcium signaling in rat aorta smooth muscle cells in response to an agonist of 5-HT2B receptors BW723C86. Biochem Biophys Res Commun. 2017 Jan 29;483(1):700-705. doi: 10.1016/j.bbrc.2016.12.079. Epub 2016 Dec 13. PubMed PMID: 27986565.

3: Blum G, Ibáñez G, Rao X, Shum D, Radu C, Djaballah H, Rice JC, Luo M. Small-molecule inhibitors of SETD8 with cellular activity. ACS Chem Biol. 2014 Nov 21;9(11):2471-8. doi: 10.1021/cb500515r. Epub 2014 Sep 3. PubMed PMID: 25137013; PubMed Central PMCID: PMC4245162.

4: Hwang BM, Chae HS, Jeong YJ, Lee YR, Noh EM, Youn HZ, Jung SH, Yu HN, Chung EY, Kim JS. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013 Nov;46(11):533-8. PubMed PMID: 24152909; PubMed Central PMCID: PMC4133842.

5: Chen W, Zhang G, Marvizón JC. NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord. Neuroscience. 2010 Mar 31;166(3):924-34. doi: 10.1016/j.neuroscience.2010.01.009. Epub 2010 Jan 13. PubMed PMID: 20074620; PubMed Central PMCID: PMC2837134.