WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563432
Description: NAEPA is a selective lysophosphatidic acid-1 (LPA1) receptor agonist and a LPA mimetic.
MedKoo Cat#: 563432
Chemical Formula: C20H40NO5P
Exact Mass: 405.2644
Molecular Weight: 405.51
Elemental Analysis: C, 59.24; H, 9.94; N, 3.45; O, 19.73; P, 7.64
IUPAC/Chemical Name: (Z)-N-[2-(Phosphonooxy)ethyl]-9-octadecenamide
InChi Key: BCSUWOZFWWBYSX-KTKRTIGZSA-N
InChi Code: InChI=1S/C20H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)21-18-19-26-27(23,24)25/h9-10H,2-8,11-19H2,1H3,(H,21,22)(H2,23,24,25)/b10-9-
SMILES Code: CCCCCCCC/C=C\CCCCCCCC(NCCOP(O)(O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 405.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Woclawek-Potocka I, Kondraciuk K, Skarzynski DJ. Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor. Exp Biol Med (Maywood). 2009 Aug;234(8):986-93. doi: 10.3181/0901-RM-36. Epub 2009 Jun 2. PubMed PMID: 19491366.
2: Sardar VM, Bautista DL, Fischer DJ, Yokoyama K, Nusser N, Virag T, Wang DA, Baker DL, Tigyi G, Parrill AL. Molecular basis for lysophosphatidic acid receptor antagonist selectivity. Biochim Biophys Acta. 2002 May 23;1582(1-3):309-17. Review. PubMed PMID: 12069842.
3: Yokoyama K, Baker DL, Virag T, Liliom K, Byun HS, Tigyi G, Bittman R. Stereochemical properties of lysophosphatidic acid receptor activation and metabolism. Biochim Biophys Acta. 2002 May 23;1582(1-3):295-308. Review. PubMed PMID: 12069841.
4: Lynch KR, Macdonald TL. Structure-activity relationships of lysophosphatidic acid analogs. Biochim Biophys Acta. 2002 May 23;1582(1-3):289-94. Review. PubMed PMID: 12069840.