Bamethanc

We are open as normal during COVID-19 pandemic. Order online, same day shipping out from North Carolina, USA

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592552

CAS#: 3703-79-5

Description: Bamethan is a Vasodilator Agent.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-20. Prices are subject to change without notice.

Bamethan is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 592552
Name: Bamethanc
CAS#: 3703-79-5
Chemical Formula: C12H19NO2
Exact Mass: 209.1416
Molecular Weight: 209.29
Elemental Analysis: C, 68.87; H, 9.15; N, 6.69; O, 15.29


Synonym: Bamethan; Butedrine; Bamethanum

IUPAC/Chemical Name: Benzenemethanol, alpha-((butylamino)methyl)-4-hydroxy-

InChi Key: RDUHXGIIUDVSHR-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H19NO2/c1-2-3-8-13-9-12(15)10-4-6-11(14)7-5-10/h4-7,12-15H,2-3,8-9H2,1H3

SMILES Code: OC(CNCCCC)C1=CC=C(O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Li T, Cao J, Li Z, Wang X, He P. Broad screening and identification of β-agonists in feed and animal body fluid and tissues using ultra-high performance liquid chromatography-quadrupole-orbitrap high resolution mass spectrometry combined with spectra library search. Food Chem. 2016 Feb 1;192:188-96. doi: 10.1016/j.foodchem.2015.06.104. Epub 2015 Jun 30. PubMed PMID: 26304337.

2: Deng Y, Zhang H, Wu JT, Olah TV. Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids. Rapid Commun Mass Spectrom. 2005;19(20):2929-34. PubMed PMID: 16175657.

3: Shou WZ, Bu HZ, Addison T, Jiang X, Naidong W. Development and validation of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of ribavirin in human plasma and serum. J Pharm Biomed Anal. 2002 Jun 20;29(1-2):83-94. PubMed PMID: 12062668.

4: Loss JR 2nd, Orzechowski RF, Hock RS. Measurement of albuterol in guinea pig serum by high performance liquid chromatography with fluorescence detection. Biomed Chromatogr. 2000 Feb;14(1):1-5. PubMed PMID: 10664547.

5: Schmid MG, Laffranchini M, Dreveny D, Gübitz G. Chiral separation of sympathomimetics by ligand exchange capillary electrophoresis. Electrophoresis. 1999 Sep;20(12):2458-61. PubMed PMID: 10499338.

6: Brambilla G, Fiori M, Curiel I, Serpe L, Gallo P. Alpha 1-acid glycoprotein affinity columns for the clean-up of adrenergic drugs. Analyst. 1998 Dec;123(12):2693-6. PubMed PMID: 10435325.

7: Armstrong DW, Rundlett K, Reid GL 3rd. Use of a macrocyclic antibiotic, rifamycin B, and indirect detection for the resolution of racemic amino alcohols by CE. Anal Chem. 1994 May 15;66(10):1690-5. PubMed PMID: 8030783.

8: Gupta RN, Fuller HD, Dolovich MB. Optimization of a column liquid chromatographic procedure for the determination of plasma salbutamol concentration. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):205-11. PubMed PMID: 8044281.

9: Kato T, Kikugawa K. Proteins and amino acids as scavengers of nitrite: inhibitory effect on the formation of nitrosodimethylamine and diazoquinone. Food Chem Toxicol. 1992 Jul;30(7):617-26. PubMed PMID: 1521836.

10: Kotwica J, Skarzyński D, Jaroszewski J. Involvement of beta-adrenoceptors in the regulation of luteal function in cattle. Br Vet J. 1991 May-Jun;147(3):189-96. PubMed PMID: 1652346.

11: Miller RB. A validated high-performance liquid chromatographic method for the determination of atenolol in whole blood. J Pharm Biomed Anal. 1991;9(10-12):849-53. PubMed PMID: 1822203.

12: Furihata C, Yamakoshi A, Matsushima T, Kato T, Kikugawa K. Possible tumour-initiating and -promoting activities of 3-diazo-N-nitrosobamethan in rat stomach mucosa. Mutagenesis. 1988 Jul;3(4):299-301. PubMed PMID: 2905413.

13: Kikugawa K, Kato T, Takeda Y. Formation of a highly mutagenic diazo compound from the bamethan-nitrite reaction. Mutat Res. 1987 Mar;177(1):35-43. PubMed PMID: 2881202.

14: Koster AS, Frankhuijzen-Sierevogel AC, Noordhoek J. Glucuronidation of morphine and six beta 2-sympathomimetics in isolated rat intestinal epithelial cells. Drug Metab Dispos. 1985 Mar-Apr;13(2):232-8. PubMed PMID: 2859174.

15: Pugliese R, Sportelli P, Sabato O, Stella M, Nazzaro P, Izzo P. [Bamethan therapy in chronic vascular insufficiency of the inferior arteries]. Clin Ter. 1982 Sep 30;102(6):599-605. Italian. PubMed PMID: 6128098.

16: Giaretti R, Astengo F, Astengo D, Coviello L, Fuliano P, Giaretti G, Melga P. [Effects of a bamethan-inositol nicotinate combination on psycho-organic disease in the elderly]. Clin Ter. 1982 Jan 31;100(2):157-65. Italian. PubMed PMID: 6137308.

17: Corti P, Sciarra G. [Use of derivative resolution for the spectrophotometric analysis of drug mixtures. I. Determination of inositol hexanicotinate and bamethan sulfate in tablets]. Boll Chim Farm. 1981 Nov;120(11):657-67. Italian. PubMed PMID: 6122456.

18: Mottolese C, Cerillo A, Falivene R, Vizioli L, Donati PA. Neri-Barré-Lieou syndrome. Nosographical arrangement and bamethan therapy results. J Neurosurg Sci. 1981 Jul-Dec;25(3-4):173-8. PubMed PMID: 6125575.

19: Cucinotta D, Silvestrini C, Mancini M, Maini C, Passeri M. [Experience with the medical treatment of chronic cerebrovascular insufficiency: bamethan and inositol nicotinate versus placebo]. G Clin Med. 1981 May;62(5):339-50. Italian. PubMed PMID: 6115790.

20: Hengstmann JH, Steinkamp B. [Pharmacokinetics of 3H-bamethan in humans]. Arzneimittelforschung. 1981;31(5):843-8. German. PubMed PMID: 6115653.