Lavendustin C6

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559038

CAS#: 144676-04-0

Description: Lavendustin C6 is a potent tyrosine kinase inhibitor.

Chemical Structure

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Lavendustin C6
CAS# 144676-04-0
Instruction

Theoretical Analysis

MedKoo Cat#: 559038
Name: Lavendustin C6
CAS#: 144676-04-0
Chemical Formula: C20H25NO5
Exact Mass: 359.17
Molecular Weight: 359.420
Elemental Analysis: C, 66.84; H, 7.01; N, 3.90; O, 22.26

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Lavendustin C6; Lavendustin C;

IUPAC/Chemical Name: 5-((2,5-dihydroxybenzyl)(hexyl)amino)-2-hydroxybenzoic acid

InChi Key: MEEQDJDRCVEZCC-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H25NO5/c1-2-3-4-5-10-21(13-14-11-16(22)7-9-18(14)23)15-6-8-19(24)17(12-15)20(25)26/h6-9,11-12,22-24H,2-5,10,13H2,1H3,(H,25,26)

SMILES Code: O=C(O)C1=CC(N(CC2=CC(O)=CC=C2O)CCCCCC)=CC=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 359.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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6: Burt HM, Jackson JK, Salari H. Inhibition of crystal-induced neutrophil activation by a protein tyrosine kinase inhibitor. J Leukoc Biol. 1994 Jan;55(1):112-9. PubMed PMID: 8283135.

7: Watanabe H, Takahashi R, Tran QK, Takeuchi K, Kosuge K, Satoh H, Uehara A, Terada H, Hayashi H, Ohno R, Ohashi K. Increased cytosolic Ca(2+) concentration in endothelial cells by calmodulin antagonists. Biochem Biophys Res Commun. 1999 Nov 30;265(3):697-702. PubMed PMID: 10600483.

8: Imoto M, Sujikai I, Ui H, Umezawa K. Involvement of tyrosine kinase in growth factor-induced phospholipase C activation in NIH3T3 cells. Biochim Biophys Acta. 1993 Feb 24;1166(2-3):188-92. PubMed PMID: 8443236.

9: Lavens-Phillips SE, Mockford EH, Warner JA. The effect of tyrosine kinase inhibitors on IgE-mediated histamine release from human lung mast cells and basophils. Inflamm Res. 1998 Mar;47(3):137-43. PubMed PMID: 9562339.