Fenazaflor
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MedKoo CAT#: 598477

CAS#: 14255-88-0

Description: Fenazaflor is used as an acaricide and insecticide.


Chemical Structure

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Fenazaflor
CAS# 14255-88-0

Theoretical Analysis

MedKoo Cat#: 598477
Name: Fenazaflor
CAS#: 14255-88-0
Chemical Formula: C15H7Cl2F3N2O2
Exact Mass: 373.98
Molecular Weight: 375.120
Elemental Analysis: C, 48.03; H, 1.88; Cl, 18.90; F, 15.19; N, 7.47; O, 8.53

Price and Availability

Size Price Availability Quantity
100mg USD 350 2 Weeks
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Synonym: Fenazaflor; Lovozal; NC 5016; NC-5016; NC5016; NSC 191025; NSC-191025; NSC191025;

IUPAC/Chemical Name: phenyl 5,6-dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole-1-carboxylate

InChi Key: ISVQSVPUDBVFFU-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H7Cl2F3N2O2/c16-9-6-11-12(7-10(9)17)22(13(21-11)15(18,19)20)14(23)24-8-4-2-1-3-5-8/h1-7H

SMILES Code: O=C(N1C2=CC(Cl)=C(Cl)C=C2N=C1C(F)(F)F)OC3=CC=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 375.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Bowker DW, Casida JE. Metabolism of the acaricide chemical, fenazaflor(5,6-dichloro-1-phenoxycarbonyl-2-trifluoromethylbenzimidazole) in certain mammals, insects, and plants. J Agric Food Chem. 1969 Sep;17(5):956-66. doi: 10.1021/jf60165a043. PubMed PMID: 21428329.

2: Weetman DF, Cain K, Sweetman AJ. The mechanism of the myocardial depression produced by congeners of the acaricide, fenazaflor. Arch Int Pharmacodyn Ther. 1973 Jun;203(2):342-7. PubMed PMID: 4270276.

3: Astashkin EN, Khodorova AB, Surin AM, Diachenko VI, Kolomiets AF, Fokin AV. [Effect of inhibitors of lipoxygenase oxidation of arachidonic acid and phenofluorazole on rat thymocyte cytoplasmic pH and on the change of this parameter induced by concanavalin A]. Dokl Akad Nauk SSSR. 1992;325(4):869-73. Russian. PubMed PMID: 8593766.

4: Astashkin EI, Surin AM, Khodorova AB, Nikolaeva IS, Diachenko VI, Kolomiets AF, Fokin AV. [Study of the effect of phenophtorazole on the calcium ion concentration in rat thymocyte cytoplasm and on changes of this parameter, induced by concanavalin A]. Dokl Akad Nauk SSSR. 1991;317(2):499-502. Russian. PubMed PMID: 1769314.