WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 461244
CAS#: 22737-97-9 (free)
Description: Zuretinol, is the metabolite of Zuretinol acetate, which is also known as QLT091001 and BBP-551, is an oral retinoid. Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
MedKoo Cat#: 461244
Name: Zuretinol
CAS#: 22737-97-9 (free)
Chemical Formula: C20H30O
Exact Mass: 286.2297
Molecular Weight: 286.45
Elemental Analysis: C, 83.86; H, 10.56; O, 5.59
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 22737-97-9 (free) 29584-22-3 (acetate)
Synonym: Zuretinol; QLT091001; QLT-091001; QLT 091001; BBP-551; BBP 551; BBP551; 9-cis-Retinal; 9-cis-Vitamin A1; Zuretinol acetate metabolite.
IUPAC/Chemical Name: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
InChi Key: FPIPGXGPPPQFEQ-MKOSUFFBSA-N
InChi Code: InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8-,17-13+
SMILES Code: CC(/C=C/C=C(\C=C\C1=C(CCCC1(C)C)C)C)=C\CO
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 286.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Hussain RM, Gregori NZ, Ciulla TA, Lam BL. Pharmacotherapy of retinal disease
with visual cycle modulators. Expert Opin Pharmacother. 2018 Apr;19(5):471-481.
doi: 10.1080/14656566.2018.1448060. Epub 2018 Mar 15. Review. PubMed PMID:
29542350.
