Laurinterol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598454

CAS#: 10539-87-4

Description: Laurinterol is an antimicrobial agent isolated from the marine alga Laurencia okamurai.


Chemical Structure

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Laurinterol
CAS# 10539-87-4

Theoretical Analysis

MedKoo Cat#: 598454
Name: Laurinterol
CAS#: 10539-87-4
Chemical Formula: C15H19BrO
Exact Mass: 294.06
Molecular Weight: 295.220
Elemental Analysis: C, 61.03; H, 6.49; Br, 27.07; O, 5.42

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Laurinterol; NSC 248546; NSC-248546; NSC248546;

IUPAC/Chemical Name: 4-bromo-2-((1R,2S,5S)-1,2-dimethylbicyclo[3.1.0]hexan-2-yl)-5-methylphenol

InChi Key: UGGAHNIITODSKB-COLVAYQJSA-N

InChi Code: InChI=1S/C15H19BrO/c1-9-6-13(17)11(7-12(9)16)14(2)5-4-10-8-15(10,14)3/h6-7,10,17H,4-5,8H2,1-3H3/t10-,14+,15+/m0/s1

SMILES Code: OC1=CC(C)=C(Br)C=C1[C@]2(C)[C@]3(C)C[C@]3([H])CC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 295.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kim MM, Mendis E, Kim SK. Laurencia okamurai extract containing laurinterol induces apoptosis in melanoma cells. J Med Food. 2008 Jun;11(2):260-6. doi: 10.1089/jmf.2007.575. PubMed PMID: 18598167.

2: Sims JJ, Donnell MS, Leary JV, Lacy GH. Antimicrobial agents from marine algae. Antimicrob Agents Chemother. 1975 Mar;7(3):320-1. PubMed PMID: 1137385; PubMed Central PMCID: PMC429132.

3: Vairappan CS, Suzuki M, Abe T, Masuda M. Halogenated metabolites with antibacterial activity from the Okinawan Laurencia species. Phytochemistry. 2001 Oct;58(3):517-23. PubMed PMID: 11557086.

4: Mao SC, Guo YW. A laurane sesquiterpene and rearranged derivatives from the Chinese red alga Laurencia okamurai Yamada. J Nat Prod. 2006 Aug;69(8):1209-11. PubMed PMID: 16933878.

5: Li XD, Miao FP, Li K, Ji NY. Sesquiterpenes and acetogenins from the marine red alga Laurencia okamurai. Fitoterapia. 2012 Apr;83(3):518-22. doi: 10.1016/j.fitote.2011.12.018. Epub 2011 Dec 30. PubMed PMID: 22233863.

6: Kawai T, Ooi T, Kusumi T. Oxidation of cyclopropane terpenoids with ruthenium tetraoxide. Chem Pharm Bull (Tokyo). 2003 Mar;51(3):291-4. PubMed PMID: 12612413.

7: Vairappan CS, Kawamoto T, Miwa H, Suzuki M. Potent antibacterial activity of halogenated compounds against antibiotic-resistant bacteria. Planta Med. 2004 Nov;70(11):1087-90. PubMed PMID: 15549668.

8: Okamoto Y, Nitanda N, Ojika M, Sakagami Y. Aplysiallene, a new bromoallene as an Na, K-ATPase inhibitor from the sea hare, Aplysia kurodai. Biosci Biotechnol Biochem. 2001 Feb;65(2):474-6. PubMed PMID: 11302194.