Lantic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598384

CAS#: 22626-26-2

Description: Lantic acid is a bioactive chemical.


Price and Availability

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Lantic acid is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 598384
Name: Lantic acid
CAS#: 22626-26-2
Chemical Formula: C30H46O4
Exact Mass: 470.3396
Molecular Weight: 470.69
Elemental Analysis: C, 76.55; H, 9.85; O, 13.60


Synonym: Lantic acid;

IUPAC/Chemical Name: (3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aS,14bS)-3-hydroxy-4,4,6a,6b,11,12-hexamethyl-2,3,4,4a,5,6,6a,7,8,9,10,11,12,12a,14,14a-hexadecahydro-1H-3,14b-(epoxymethano)picene-8a(6bH)-carboxylic acid

InChi Key: WFSVWMKYCNCEAW-MFTKVSCJSA-N

InChi Code: InChI=1S/C30H46O4/c1-18-9-12-28(24(31)32)14-13-26(5)20(23(28)19(18)2)7-8-22-27(26,6)11-10-21-25(3,4)30(33)16-15-29(21,22)17-34-30/h7,18-19,21-23,33H,8-17H2,1-6H3,(H,31,32)/t18-,19+,21+,22+,23+,26-,27-,28+,29-,30+/m1/s1

SMILES Code: CC1(C)[C@]2(O)CC[C@]3(CO2)[C@@]4([H])CC=C5[C@]6([H])[C@@H](C)[C@H](C)CC[C@@](C(O)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

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2: Subramanian MR, Talluri S, Christopher LP. Production of lactic acid using a new homofermentative Enterococcus faecalis isolate. Microb Biotechnol. 2015 Mar;8(2):221-9. doi: 10.1111/1751-7915.12133. Epub 2014 Jun 3. PubMed PMID: 24894833; PubMed Central PMCID: PMC4353336.

3: Wijayasinghe R, Vasiljevic T, Chandrapala J. Water-lactose behavior as a function of concentration and presence of lactic acid in lactose model systems. J Dairy Sci. 2015 Dec;98(12):8505-14. doi: 10.3168/jds.2015-9959. Epub 2015 Oct 23. PubMed PMID: 26476948.

4: Dreschke G, Probst M, Walter A, Pümpel T, Walde J, Insam H. Lactic acid and methane: improved exploitation of biowaste potential. Bioresour Technol. 2015 Jan;176:47-55. doi: 10.1016/j.biortech.2014.10.136. Epub 2014 Nov 4. PubMed PMID: 25460983.

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7: Li J, Zhu C, Tu M, Han P, Wu Y. Effect of carbonyl inhibitors and their H₂O₂ detoxification on lactic acid fermentation. Appl Biochem Biotechnol. 2015 Apr;175(8):3657-72. doi: 10.1007/s12010-015-1533-2. Epub 2015 Feb 11. PubMed PMID: 25666370.

8: Wang J, Wang Q, Xu Z, Zhang W, Xiang J. Effect of fermentation conditions on L-lactic acid production from soybean straw hydrolysate. J Microbiol Biotechnol. 2015 Jan;25(1):26-32. PubMed PMID: 25152056.

9: Yao J, Zhang Y, Zhang J, Yang X. [Effect of Lactobacillus acidophilus on metabolizing lactic acid in formula milk: a quantitative analysis of the effect of erythritol]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2015 Jul;50(7):408-12. Chinese. PubMed PMID: 26564744.

10: Gong Z, Luna Y, Yu P, Fan H. Lactobacilli inactivate Chlamydia trachomatis through lactic acid but not H2O2. PLoS One. 2014 Sep 12;9(9):e107758. doi: 10.1371/journal.pone.0107758. eCollection 2014. PubMed PMID: 25215504; PubMed Central PMCID: PMC4162611.

11: Pavot V, Berthet M, Rességuier J, Legaz S, Handké N, Gilbert SC, Paul S, Verrier B. Poly(lactic acid) and poly(lactic-co-glycolic acid) particles as versatile carrier platforms for vaccine delivery. Nanomedicine (Lond). 2014 Dec;9(17):2703-18. doi: 10.2217/nnm.14.156. PubMed PMID: 25529572.

12: Wang Y, Tashiro Y, Sonomoto K. Fermentative production of lactic acid from renewable materials: recent achievements, prospects, and limits. J Biosci Bioeng. 2015 Jan;119(1):10-8. doi: 10.1016/j.jbiosc.2014.06.003. Epub 2014 Jul 27. Review. PubMed PMID: 25077706.

13: Hama S, Mizuno S, Kihara M, Tanaka T, Ogino C, Noda H, Kondo A. Production of d-lactic acid from hardwood pulp by mechanical milling followed by simultaneous saccharification and fermentation using metabolically engineered Lactobacillus plantarum. Bioresour Technol. 2015;187:167-172. doi: 10.1016/j.biortech.2015.03.106. Epub 2015 Mar 28. PubMed PMID: 25846187.

14: Liguori R, Soccol CR, Vandenberghe LP, Woiciechowski AL, Ionata E, Marcolongo L, Faraco V. Selection of the Strain Lactobacillus acidophilus ATCC 43121 and Its Application to Brewers' Spent Grain Conversion into Lactic Acid. Biomed Res Int. 2015;2015:240231. doi: 10.1155/2015/240231. Epub 2015 Nov 10. PubMed PMID: 26640784; PubMed Central PMCID: PMC4657078.

15: Oh JH, Vinay-Lara E, McMinn R Jr, Glass KA, Johnson ME, Steele JL. Evaluation of NaCl, pH, and lactic acid on the growth of Shiga toxin-producing Escherichia coli in a liquid Cheddar cheese extract. J Dairy Sci. 2014 Nov;97(11):6671-9. doi: 10.3168/jds.2014-7946. Epub 2014 Sep 6. PubMed PMID: 25200778.

16: Lee YS, Naning KW, Nguyen XH, Kim SB, Moon JH, Kim KY. Ovicidal activity of lactic acid produced by Lysobacter capsici YS1215 on eggs of root-knot nematode, Meloidogyne incognita. J Microbiol Biotechnol. 2014 Nov 28;24(11):1510-5. PubMed PMID: 25085571.

17: Kumar MN, Gialleli AI, Masson JB, Kandylis P, Bekatorou A, Koutinas AA, Kanellaki M. Lactic acid fermentation by cells immobilised on various porous cellulosic materials and their alginate/poly-lactic acid composites. Bioresour Technol. 2014 Aug;165:332-5. doi: 10.1016/j.biortech.2014.02.110. Epub 2014 Mar 5. PubMed PMID: 24690466.

18: Breithaupt A, Fitzgerald R. Collagen Stimulators: Poly-L-Lactic Acid and Calcium Hydroxyl Apatite. Facial Plast Surg Clin North Am. 2015 Nov;23(4):459-69. doi: 10.1016/j.fsc.2015.07.007. Review. PubMed PMID: 26505542.

19: Abdel-Rahman MA, Tashiro Y, Sonomoto K. Recent advances in lactic acid production by microbial fermentation processes. Biotechnol Adv. 2013 Nov;31(6):877-902. doi: 10.1016/j.biotechadv.2013.04.002. Epub 2013 Apr 24. Review. PubMed PMID: 23624242.

20: Joseph A, Aikawa S, Sasaki K, Tsuge Y, Matsuda F, Tanaka T, Kondo A. Utilization of lactic acid bacterial genes in Synechocystis sp. PCC 6803 in the production of lactic acid. Biosci Biotechnol Biochem. 2013;77(5):966-70. Epub 2013 May 7. PubMed PMID: 23649263.