Lanomycin

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MedKoo CAT#: 598305

CAS#: 141363-91-9

Description: Lanomycin is isolated from Pycnidiophora dispersa; inhibits lanosterol 14alpha-demethylase.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-10. Prices are subject to change without notice.

Lanomycin is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 598305
Name: Lanomycin
CAS#: 141363-91-9
Chemical Formula: C17H27NO4
Exact Mass: 309.194
Molecular Weight: 309.4
Elemental Analysis: C, 65.99; H, 8.80; N, 4.53; O, 20.68


Synonym: Lanomycin;

IUPAC/Chemical Name: (2R,3S,4R,5R)-4-methoxy-5-methyl-2-((2E,4E,6E)-octa-2,4,6-trien-2-yl)tetrahydro-2H-pyran-3-yl glycinate

InChi Key: DMLQRXAYJODTLF-XNMVBDESSA-N

InChi Code: InChI=1S/C17H27NO4/c1-5-6-7-8-9-12(2)16-17(22-14(19)10-18)15(20-4)13(3)11-21-16/h5-9,13,15-17H,10-11,18H2,1-4H3/b6-5+,8-7+,12-9+/t13-,15-,16-,17+/m1/s1

SMILES Code: NCC(O[C@@H]1[C@@H](/C(C)=C/C=C/C=C/C)OC[C@@H](C)[C@H]1OC)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: O'Sullivan J, Phillipson DW, Kirsch DR, Fisher SM, Lai MH, Trejo WH. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. I. Discovery, isolation and biological activity. J Antibiot (Tokyo). 1992 Mar;45(3):306-12. PubMed PMID: 1577658.

2: Remsburg B, Phillipson DW, O'Sullivan J. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. III. Biosynthesis of lanomycin: 13C NMR assignment and origin of the carbon skeleton. J Antibiot (Tokyo). 1992 Mar;45(3):420-3. PubMed PMID: 1577669.

3: Phillipson DW, O'Sullivan J, Johnson JH, Bolgar MS, Kahle AD. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. II. Structure elucidation. J Antibiot (Tokyo). 1992 Mar;45(3):313-9. PubMed PMID: 1577659.