PA Autoinducer

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MedKoo CAT#: 563421

CAS#: 152833-54-0

Description: PA Autoinducer is a Pseudomonas aeruginosa autoinducer.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-14. Prices are subject to change without notice.

PA Autoinducer is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 563421
Name: PA Autoinducer
CAS#: 152833-54-0
Chemical Formula: C16H27NO4
Exact Mass: 297.194
Molecular Weight: 297.39
Elemental Analysis: C, 64.62; H, 9.15; N, 4.71; O, 21.52

Synonym: PA Autoinducer; PA-Autoinducer; 3O-C12 autoinducer;

IUPAC/Chemical Name: N-(3-Oxododecanoyl)homoserine lactone


InChi Code: InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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8: Eum SY, Jaraki D, Bertrand L, András IE, Toborek M. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases. Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G992-G1001. doi: 10.1152/ajpgi.00016.2014. Epub 2014 Apr 17. PubMed PMID: 24742991; PubMed Central PMCID: PMC4042118.

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13: Hosono Honda N, Kimura S, Tateda K, Horikawa M, Ueda C, Ishii Y, Ishiguro M, Miyairi S, Yamaguchi K. Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches. Microbes Environ. 2011;26(2):160-4. Epub 2011 Mar 29. PubMed PMID: 21502732.

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15: Mayer ML, Sheridan JA, Blohmke CJ, Turvey SE, Hancock RE. The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells. PLoS One. 2011 Jan 31;6(1):e16246. doi: 10.1371/journal.pone.0016246. PubMed PMID: 21305014; PubMed Central PMCID: PMC3031552.

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19: Kristiansen S, Bjarnsholt T, Adeltoft D, Ifversen P, Givskov M. The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells. APMIS. 2008 May;116(5):361-71. doi: 10.1111/j.1600-0463.2008.00966.x. PubMed PMID: 18452426.

20: Jahoor A, Patel R, Bryan A, Do C, Krier J, Watters C, Wahli W, Li G, Williams SC, Rumbaugh KP. Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer. J Bacteriol. 2008 Jul;190(13):4408-15. doi: 10.1128/JB.01444-07. Epub 2008 Jan 4. PubMed PMID: 18178738; PubMed Central PMCID: PMC2446782.