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MedKoo CAT#: 598296

CAS#: 23623-31-6

Description: Lankacidins is an antitumor antibiotic of the macrolide tetraenes family, isolated from Streptomyces.

Price and Availability

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Pricing updated 2020-08-15. Prices are subject to change without notice.

Lankacidins is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 598296
Name: Lankacidins
CAS#: 23623-31-6
Chemical Formula: C25H33NO7
Exact Mass: 459.2257
Molecular Weight: 459.53
Elemental Analysis: C, 65.34; H, 7.24; N, 3.05; O, 24.37

Synonym: Lankacidins; Lankacidin C; Lankacidin; Antibiotic T-2636 C; Bundlin A; NSC 145118; NSC-145118; NSC145118; T-2636C; T 2636C; T2636C;

IUPAC/Chemical Name: N-((1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl)-2-oxopropanamide


InChi Code: InChI=1S/C25H33NO7/c1-14-6-9-18(28)10-8-15(2)12-21(26-23(31)17(4)27)25(5)22(30)16(3)20(33-24(25)32)13-19(29)11-7-14/h6-8,10-12,16,18-21,28-29H,9,13H2,1-5H3,(H,26,31)/b10-8+,11-7+,14-6+,15-12+/t16-,18+,19-,20-,21-,25+/m1/s1

SMILES Code: CC(C(N[C@H](/C=C(C)/C=C/[C@@H](O)C/C=C(C)/C=C/[C@@H](O)C[C@@]1([H])O2)[C@](C([C@@H]1C)=O)(C)C2=O)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


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7: Arakawa K, Tsuda N, Taniguchi A, Kinashi H. The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. Chembiochem. 2012 Jul 9;13(10):1447-57. doi: 10.1002/cbic.201200149. Epub 2012 Jun 14. PubMed PMID: 22761035.

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15: Tatsuno S, Arakawa K, Kinashi H. Analysis of modular-iterative mixed biosynthesis of lankacidin by heterologous expression and gene fusion. J Antibiot (Tokyo). 2007 Nov;60(11):700-8. PubMed PMID: 18057700.

16: Sawada H, Suzuki T, Akiyama S, Nakao Y. Mechanism of the stimulatory effect of cyclodextrins on lankacidin-producing Streptomyces. Appl Microbiol Biotechnol. 1990 Feb;32(5):556-9. PubMed PMID: 1366439.

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