1-Heptanone, 1-(4-pyridyl)-

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558469

CAS#: 32941-30-3

Description: 1-Heptanone, 1-(4-pyridyl)- is a bioactive chemical.


Chemical Structure

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1-Heptanone, 1-(4-pyridyl)-
CAS# 32941-30-3

Theoretical Analysis

MedKoo Cat#: 558469
Name: 1-Heptanone, 1-(4-pyridyl)-
CAS#: 32941-30-3
Chemical Formula: C12H17NO
Exact Mass: 191.13
Molecular Weight: 191.270
Elemental Analysis: C, 75.35; H, 8.96; N, 7.32; O, 8.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: 1-Heptanone, 1-(4-pyridyl)-; 1-(4-Pyridyl)-1-heptanone; 4-Heptanoylpyridine;

IUPAC/Chemical Name: 1-Heptanone, 1-(4-pyridyl)-

InChi Key: MLBWTXHUVGBPNL-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H17NO/c1-2-3-4-5-6-12(14)11-7-9-13-10-8-11/h7-10H,2-6H2,1H3

SMILES Code: CCCCCCC(C1=CC=NC=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 191.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Qian C, Ren N, Wang J, Xu Q, Chen X, Qi X. Effects of exogenous application of CPPU, NAA and GA(4+7) on parthenocarpy and fruit quality in cucumber (Cucumis sativus L.). Food Chem. 2018 Mar 15;243:410-413. doi: 10.1016/j.foodchem.2017.09.150. Epub 2017 Sep 30. PubMed PMID: 29146357.

2: Morsali A, Hosseini-Monfared H, Morsali A, Mayer P. Sonochemical synthesis and characterization of new one-dimensional manganese(II) coordination polymer nanostructures. Ultrason Sonochem. 2015 May;24:140-5. doi: 10.1016/j.ultsonch.2014.11.011. Epub 2014 Nov 23. PubMed PMID: 25483353.

3: Liu H, Lv C, Ding B, Wang J, Li S, Zhang Y. Antitumor activity of G-quadruplex-interactive agent TMPyP4 with photodynamic therapy in ovarian carcinoma cells. Oncol Lett. 2014 Jul;8(1):409-413. Epub 2014 May 8. PubMed PMID: 24959286; PubMed Central PMCID: PMC4063630.

4: Kabeya LM, Fuzissaki CN, Taleb-Contini SH, da C Ferreira AM, Naal Z, Santos EO, Figueiredo-Rinhel AS, Azzolini AE, Vermelho RB, Malvezzi A, Amaral AT, Lopes JL, Lucisano-Valim YM. 7-Hydroxycoumarin modulates the oxidative metabolism, degranulation and microbial killing of human neutrophils. Chem Biol Interact. 2013 Oct 25;206(1):63-75. doi: 10.1016/j.cbi.2013.08.010. Epub 2013 Aug 28. PubMed PMID: 23994743.

5: Kidd M, Modlin IM, Bodei L, Drozdov I. Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology. Cell Mol Gastroenterol Hepatol. 2015 Jan 12;1(2):131-153. doi: 10.1016/j.jcmgh.2014.12.008. eCollection 2015 Mar. Review. PubMed PMID: 28210673; PubMed Central PMCID: PMC5301133.

6: Gao XH, Qanungo S, Pai HV, Starke DW, Steller KM, Fujioka H, Lesnefsky EJ, Kerner J, Rosca MG, Hoppel CL, Mieyal JJ. Aging-dependent changes in rat heart mitochondrial glutaredoxins--Implications for redox regulation. Redox Biol. 2013 Nov 12;1:586-98. doi: 10.1016/j.redox.2013.10.010. eCollection 2013. PubMed PMID: 25126518; PubMed Central PMCID: PMC4127417.

7: Qin H, Huang CH, Mao L, Xia HY, Kalyanaraman B, Shao J, Shan GQ, Zhu BZ. Molecular mechanism of metal-independent decomposition of lipid hydroperoxide 13-HPODE by halogenated quinoid carcinogens. Free Radic Biol Med. 2013 Oct;63:459-66. doi: 10.1016/j.freeradbiomed.2013.05.008. Epub 2013 May 14. PubMed PMID: 23680403; PubMed Central PMCID: PMC5806606.

8: Gao YB, Wang CL, Wu JY, Zhou HS, Jiang XT, Wu J, Zhang SL. Low temperature inhibits pollen tube growth by disruption of both tip-localized reactive oxygen species and endocytosis in Pyrus bretschneideri Rehd. Plant Physiol Biochem. 2014 Jan;74:255-62. doi: 10.1016/j.plaphy.2013.11.018. Epub 2013 Nov 25. PubMed PMID: 24321875.

9: Thomas AH, Serrano MP, Rahal V, Vicendo P, Claparols C, Oliveros E, Lorente C. Tryptophan oxidation photosensitized by pterin. Free Radic Biol Med. 2013 Oct;63:467-75. doi: 10.1016/j.freeradbiomed.2013.05.044. Epub 2013 Jun 5. PubMed PMID: 23747929.

10: Xu Y, Qi J, Yang X, Wu E, Qian SY. Free radical derivatives formed from cyclooxygenase-catalyzed dihomo-γ-linolenic acid peroxidation can attenuate colon cancer cell growth and enhance 5-fluorouracil's cytotoxicity. Redox Biol. 2014 Mar 20;2:610-8. doi: 10.1016/j.redox.2014.01.022. eCollection 2014. PubMed PMID: 25114837; PubMed Central PMCID: PMC4124262.

11: Hawkins CL, Davies MJ. Detection and characterisation of radicals in biological materials using EPR methodology. Biochim Biophys Acta. 2014 Feb;1840(2):708-21. doi: 10.1016/j.bbagen.2013.03.034. Epub 2013 Apr 6. Review. PubMed PMID: 23567797.

12: Leinisch F, Jiang J, DeRose EF, Khramtsov VV, Mason RP. Investigation of spin-trapping artifacts formed by the Forrester-Hepburn mechanism. Free Radic Biol Med. 2013 Dec;65:1497-505. doi: 10.1016/j.freeradbiomed.2013.07.006. Epub 2013 Jul 10. PubMed PMID: 23851031; PubMed Central PMCID: PMC3859841.

13: Elsayed NH, Monier M, Youssef I. Fabrication of photo-active trans-3-(4-pyridyl)acrylic acid modified chitosan. Carbohydr Polym. 2017 Sep 15;172:1-10. doi: 10.1016/j.carbpol.2017.04.072. Epub 2017 Apr 24. PubMed PMID: 28606514.

14: Yaku H, Murashima T, Tateishi-Karimata H, Nakano S, Miyoshi D, Sugimoto N. Study on effects of molecular crowding on G-quadruplex-ligand binding and ligand-mediated telomerase inhibition. Methods. 2013 Nov;64(1):19-27. doi: 10.1016/j.ymeth.2013.03.028. Epub 2013 Apr 2. PubMed PMID: 23562626.

15: Chen S, Su L, Qiu J, Xiao N, Lin J, Tan JH, Ou TM, Gu LQ, Huang ZS, Li D. Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription. Biochim Biophys Acta. 2013 Oct;1830(10):4769-77. doi: 10.1016/j.bbagen.2013.06.007. Epub 2013 Jun 14. PubMed PMID: 23774591.

16: Rees MD, Dang L, Thai T, Owen DM, Malle E, Thomas SR. Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells. Free Radic Biol Med. 2012 Dec 15;53(12):2344-56. doi: 10.1016/j.freeradbiomed.2012.10.002. Epub 2012 Oct 9. PubMed PMID: 23059132; PubMed Central PMCID: PMC3529214.

17: Zhang T, Lv Y, Lei Y, Liu D, Feng Y, Zhao J, Chen S, Meng F, Wang S. Design, synthesis and biological evaluation of 1-hydroxy-2-phenyl-4-pyridyl-1H-imidazole derivatives as xanthine oxidase inhibitors. Eur J Med Chem. 2018 Feb 25;146:668-677. doi: 10.1016/j.ejmech.2018.01.060. Epub 2018 Jan 31. PubMed PMID: 29407989.

18: Ionescu RE, Aybeke EN, Bourillot E, Lacroute Y, Lesniewska E, Adam PM, Bijeon JL. Fabrication of Annealed Gold Nanostructures on Pre-Treated Glow-Discharge Cleaned Glasses and Their Used for Localized Surface Plasmon Resonance (LSPR) and Surface Enhanced Raman Spectroscopy (SERS) Detection of Adsorbed (Bio)molecules. Sensors (Basel). 2017 Jan 26;17(2). pii: E236. doi: 10.3390/s17020236. PubMed PMID: 28134754; PubMed Central PMCID: PMC5336031.