Lagunamycin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598233

CAS#: 150693-65-5

Description: Lagunamycin is a novel 5-lipoxygenase inhibitor.


Chemical Structure

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Lagunamycin
CAS# 150693-65-5

Theoretical Analysis

MedKoo Cat#: 598233
Name: Lagunamycin
CAS#: 150693-65-5
Chemical Formula: C13H10O6
Exact Mass: 262.05
Molecular Weight: 262.210
Elemental Analysis: C, 59.55; H, 3.84; O, 36.61

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Lagunamycin;

IUPAC/Chemical Name: (3,4-dihydroxyphenyl)(2,4,6-trihydroxyphenyl)methanone

InChi Key: XNWPXDGRBWJIES-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H10O6/c14-7-4-10(17)12(11(18)5-7)13(19)6-1-2-8(15)9(16)3-6/h1-5,14-18H

SMILES Code: O=C(C1=CC=C(O)C(O)=C1)C2=C(O)C=C(O)C=C2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Nihei Y, Hasegawa M, Suzuki K, Yamamoto S, Hanada M, Furumai T, Fukagawa Y, Oki T. Lagunamycin, a novel 5-lipoxygenase inhibitor. I. Taxonomy, fermentation, physico-chemical properties and biological characteristics. J Antibiot (Tokyo). 1993 Jun;46(6):900-7. PubMed PMID: 8393850.

2: Imae K, Nihei Y, Oka M, Yamasaki T, Konishi M, Oki T. Lagunamycin, a novel 5-lipoxygenase inhibitor. II. Structural studies. J Antibiot (Tokyo). 1993 Jun;46(6):1031-3. PubMed PMID: 8393849.

3: Tatsuta K, Hosokawa S. Total syntheses of polyketide-derived bioactive natural products. Chem Rec. 2006;6(4):217-33. Review. PubMed PMID: 16900486.

4: Díaz-Cárdenas C, Cantillo A, Rojas LY, Sandoval T, Fiorentino S, Robles J, Ramos FA, Zambrano MM, Baena S. Microbial diversity of saline environments: searching for cytotoxic activities. AMB Express. 2017 Dec 22;7(1):223. doi: 10.1186/s13568-017-0527-6. Erratum in: AMB Express. 2018 Mar 9;8(1):35. PubMed PMID: 29273919; PubMed Central PMCID: PMC5741568.