8-Br-cGMP
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MedKoo CAT#: 563397

CAS#: 51116-01-9

Description: 8-Br-cGMP is an activator of cGMP-dependent protein kinase. It acts by inhibiting the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine.

Chemical Structure

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8-Br-cGMP
CAS# 51116-01-9
Instruction

Theoretical Analysis

MedKoo Cat#: 563397
Name: 8-Br-cGMP
CAS#: 51116-01-9
Chemical Formula: C10H10BrN5NaO7P
Exact Mass: 444.94
Molecular Weight: 446.080
Elemental Analysis: C, 26.93; H, 2.26; Br, 17.91; N, 15.70; Na, 5.15; O, 25.11; P, 6.94

Price and Availability

Size Price Availability Quantity
10mg USD 230
25mg USD 400
50mg USD 660
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Synonym: 8-Br-cGMP; 8 Br cGMP; 8BrcGMP;

IUPAC/Chemical Name: sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide

InChi Key: ZJRFCXHKYQVNFK-YEOHUATISA-M

InChi Code: InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1

SMILES Code: [H][C@@]12COP([O-])(O[C@]1([C@H]([C@H](N3C(Br)=NC4=C3NC(N)=NC4=O)O2)O)[H])=O.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 446.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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