Dansylhydrazide trivaline

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MedKoo CAT#: 598131

CAS#: 76080-91-6

Description: Dansylhydrazide trivaline is a bioactive chemical that can exhibit florescence.


Price and Availability

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Pricing updated 2020-07-11. Prices are subject to change without notice.

Dansylhydrazide trivaline is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 598131
Name: Dansylhydrazide trivaline
CAS#: 76080-91-6
Chemical Formula: C27H42N6O5S
Exact Mass: 562.2937
Molecular Weight: 562.73
Elemental Analysis: C, 57.63; H, 7.52; N, 14.93; O, 14.22; S, 5.70


Synonym: Dansylhydrazide trivaline; DGTV; H-Val-val-val-N2H2-dns;

IUPAC/Chemical Name: (S)-2-amino-N-((S)-1-(((S)-1-(2-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)hydrazinyl)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-3-methylbutanamide

InChi Key: AWIZJVIMVDVVFV-HJOGWXRNSA-N

InChi Code: InChI=1S/C27H42N6O5S/c1-15(2)22(28)25(34)29-23(16(3)4)26(35)30-24(17(5)6)27(36)31-32-39(37,38)21-14-10-11-18-19(21)12-9-13-20(18)33(7)8/h9-17,22-24,32H,28H2,1-8H3,(H,29,34)(H,30,35)(H,31,36)/t22-,23-,24-/m0/s1

SMILES Code: CC(C)[C@@H](C(NNS(=O)(C1=C2C=CC=C(N(C)C)C2=CC=C1)=O)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)N)=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Streltsov SA, Martinkina LP, Vengerov YYu. Concatemerization of tRNA molecules in the presence of trivaline derivative. FEBS Lett. 1999 Feb 12;444(2-3):231-4. PubMed PMID: 10050765.

2: Martinkina LP, Novikova EG, Streltsov SA, Kolesnikov AA, Vengerov YYu. Structural organization of kinetoplast DNA and its compaction in the in vitro model system. Eur J Cell Biol. 1991 Oct;56(1):123-31. PubMed PMID: 1800112.

3: Strel'tsov SA, Vorodina MV, Nechipurenko IuN, Semenov TE. [Trivaline initiates formation of homo- and heteroquadruplex DNA structures]. Biofizika. 1997 Mar-Apr;42(2):378-88. Russian. PubMed PMID: 9172683.

4: Streltsov SA, Semenov TE, Moroz OV. Homology in trivaline complex formation with dsDNA and ssRNA. J Biomol Struct Dyn. 1993 Feb;10(4):763-84. PubMed PMID: 7682081.

5: Klinov DV, Martynkina LP, Iurchenko VIu, Demin VV, Strel'tsov SA, Gerasimov IuA, Vengerov IuIu. [Effect of supporting substrates on the structure of DNA and DNA-trivaline complexes studied by atomic force microscopy]. Bioorg Khim. 2003 Jul-Aug;29(4):397-402. Russian. PubMed PMID: 12947761.

6: Makarov VL, Strel'tsov SA, Vengerov IuIu, Khorlin AA, Gurskiĭ GV. [Spatial structure of DNA complex with the oligopeptide dansyl hydrazide trivaline]. Mol Biol (Mosk). 1983 Sep-Oct;17(5):1089-102. Russian. PubMed PMID: 6633529.

7: Strel'tsov SA, Lysov IuP, Semenov TE, Vengerov IuIu, Khorlin AA, Surovaia AN, Gurskiĭ GV. [Interaction of trivaline with single-stranded polyribonucleotides]. Mol Biol (Mosk). 1991 Jul-Aug;25(4):1040-60. Russian. PubMed PMID: 1795699.

8: Streltsov SA, Martinkina LP, Khorlin AA, Florentiev VL, Vengerov YYu, Zhenodarova SM, Sedelnikova EA, Smolyaninova OA. Trivaline molecular complexes with trinucleotides form in solution the extended, about 1000 A in length structures. J Biomol Struct Dyn. 1994 Jun;11(6):1403-15. PubMed PMID: 7946081.

9: Vengerov YY, Semenov TE, Streltsov SA, Makarov VL, Khorlin AA, Gursky GV. Triple rings: a new type of compact structure of circular DNA. J Mol Biol. 1985 Jul 20;184(2):251-5. PubMed PMID: 4032479.

10: Vengerov IuIu, Semenov TE, Strel'tsov SA, Makarov VL, Khorlin AA. [Intramolecular compactization of circular DNA in interaction with dansyl hydrazide trivaline leading to a formation of a new type of structure--triple rings]. Mol Biol (Mosk). 1985 Sep-Oct;19(5):1223-30. Russian. PubMed PMID: 4079921.

11: Martynkina LP, Novikova EG, Kolesnikov AA, Strel'tsov SA, Semenov TE, Vengerov IuIu. [Structural organization of kinetoplast DNA and its compactization in a model system in vitro]. Mol Biol (Mosk). 1989 Nov-Dec;23(6):1645-57. Russian. PubMed PMID: 2561179.

12: Strel'tsov SA, Khorlin AA, Surovaia AN, Gurskiĭ GV, Zasedatelev AS. [Specific reaction between oligovaline and nucleic acids]. Biofizika. 1980 Sep-Oct;25(5):929-41. Russian. PubMed PMID: 7417586.

13: Vengerov YY, Semenov TE, Streltsov SA, Makarov VL, Khorlin AA, Gursky GV. Torus-shaped particles formed due to intermolecular condensation of circular DNA upon interaction with synthetic tripeptide. FEBS Lett. 1985 Jan 21;180(1):81-4. PubMed PMID: 3967760.