C-333H

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598042

CAS#: 870095-15-1

Description: C-333H is a novel PPARalpha/gamma dual agonist.


Price and Availability

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C-333H is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 598042
Name: C-333H
CAS#: 870095-15-1
Chemical Formula: C28H26N2O6
Exact Mass: 486.1791
Molecular Weight: 486.52
Elemental Analysis: C, 69.12; H, 5.39; N, 5.76; O, 19.73


Synonym: C-333H; C 333H; C333H;

IUPAC/Chemical Name: (S,E)-2-(3-(furan-2-yl)acrylamido)-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid

InChi Key: YHBKSRJCMFFFMB-AAJFVQQISA-N

InChi Code: InChI=1S/C28H26N2O6/c1-19-24(30-27(36-19)21-6-3-2-4-7-21)15-17-35-23-11-9-20(10-12-23)18-25(28(32)33)29-26(31)14-13-22-8-5-16-34-22/h2-14,16,25H,15,17-18H2,1H3,(H,29,31)(H,32,33)/b14-13+/t25-/m0/s1

SMILES Code: O=C(O)[C@H](CC1=CC=C(OCCC2=C(C)OC(C3=CC=CC=C3)=N2)C=C1)NC(/C=C/C4=CC=CO4)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Zhang N, Chen W, Zhou X, Zhou X, Xie X, Meng A, Li S, Wang L. C333H ameliorated insulin resistance through selectively modulating peroxisome proliferator-activated receptor γ in brown adipose tissue of db/db mice. Biol Pharm Bull. 2013;36(6):980-7. Epub 2013 Apr 6. PubMed PMID: 23563593.

2: Xu C, Wang LL, Liu HY, Zhou XB, Cao YL, Li S. C333H, a novel PPARalpha/gamma dual agonist, has beneficial effects on insulin resistance and lipid metabolism. Acta Pharmacol Sin. 2006 Feb;27(2):223-8. PubMed PMID: 16412273.