Pam 1392

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MedKoo CAT#: 592296

CAS#: 13794-65-5

Description: Pam 1392 is a chemotherapeutic agent.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-10. Prices are subject to change without notice.

Pam 1392 purity > 98%, is in stock. The same day shipping out after order is received. Note: the estimated shipping out time for order > 200mg may be 2 weeks.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 592296
Name: Pam 1392
CAS#: 13794-65-5
Chemical Formula: C15H15CL2N5
Exact Mass: 333.0548
Molecular Weight: 334.2
Elemental Analysis: C, 53.91; H, 3.92; Cl, 21.21; N, 20.96


Synonym: Pam 1392; AI3-52841; AI3 52841; AI352841

IUPAC/Chemical Name: 2,4,6-Quinazolinetriamine, N6-((3,4-dichlorophenyl)methyl)-

InChi Key: LTSQDQVTNREIAO-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H13Cl2N5/c16-11-3-1-8(5-12(11)17)7-20-9-2-4-13-10(6-9)14(18)22-15(19)21-13/h1-6,20H,7H2,(H4,18,19,21,22)

SMILES Code: NC1=NC(N)=C2C=C(NCC3=CC=C(Cl)C(Cl)=C3)C=CC2=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Matsui T, Tasaki M, Yoshioka T, Motoki Y, Tsuneoka H, Nojima J. Temperature- and time-dependent changes in TLR2-activated microglial NF-κB activity and concentrations of inflammatory and anti-inflammatory factors. Intensive Care Med. 2012 Aug;38(8):1392-9. doi: 10.1007/s00134-012-2591-3. Epub 2012 Jun 1. PubMed PMID: 22653369.

2: Shepard CC. Further experience with the kinetic method for the study of drugs against Mycobacterium leprae in mice. Activities of DDS, DFD, ethionamide, capreomycin and PAM 1392. Int J Lepr Other Mycobact Dis. 1969 Oct-Dec;37(4):389-97. PubMed PMID: 4918202.

3: Thompson PE, Bayles A, Olszewski B. PAM 1392 (2,4-diamino-6-(3,4-dichlorobenzylamino) quinazoline) as a chemotherapeutic agent: Plasmodium berghei, P. cynomolgi, P. Exp Parasitol. 1969 Aug;25(1):32-49. PubMed PMID: 4983051.