Xanthine
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MedKoo CAT#: 592258

CAS#: 69-89-6

Description: Xanthine is a purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects.


Price and Availability

Size
Price

5g
USD 270
Size
Price

10g
USD 430
Size
Price

25g
USD 710

Xanthine purity > 98%, is in stock. The same day shipping out after order is received. Note: the estimated shipping out time for order > 200mg may be 2 weeks.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 592258
Name: Xanthine
CAS#: 69-89-6
Chemical Formula: C5H4N4O2
Exact Mass: 152.0334
Molecular Weight: 152.11
Elemental Analysis: C, 39.48; H, 2.65; N, 36.83; O, 21.04


Synonym: Xanthine

IUPAC/Chemical Name: 1H-Purine-2,6-dione, 3,7-dihydro-

InChi Key: LRFVTYWOQMYALW-UHFFFAOYSA-N

InChi Code: InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

SMILES Code: O=C(N1)NC2=C(NC=N2)C1=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK501476/ PubMed PMID: 30000536.

2: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK501467/ PubMed PMID: 30000527.

3: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK501382/ PubMed PMID: 30000441.

4: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from http://www.ncbi.nlm.nih.gov/books/NBK501109/ PubMed PMID: 30000168.

5: Omolekulo TE, Areola ED, Badmus OO, Michael OS, Kim I, Olatunji LA. Adenosine deaminase and xanthine oxidase inhibitory effect of valproic acid abates glucose dysregulation and liver triglyceride accumulation independent of corticosteroids in estrogen/progestin-treated female rats. Can J Physiol Pharmacol. 2018 Jul 12. doi: 10.1139/cjpp-2018-0231. [Epub ahead of print] PubMed PMID: 30001502.

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9: Sugahara S, Chiyo A, Fukuoka K, Ueda Y, Tokunaga Y, Nishida Y, Kinoshita H, Matsuda Y, Igoshi K, Ono M, Yasuda S. Unique antioxidant effects of herbal leaf tea and stem tea from Moringa oleifera L. especially on superoxide anion radical generation systems. Biosci Biotechnol Biochem. 2018 Jul 11:1-12. doi: 10.1080/09168451.2018.1495552. [Epub ahead of print] PubMed PMID: 29993353.

10: Kopiec G, Starzec K, Kochana J, Kinnunen-Skidmore TP, Schuhmann W, Campbell WH, Ruff A, Plumeré N. Bioelectrocatalytic and electrochemical cascade for phosphate sensing with up to 6 electrons per analyte molecule. Biosens Bioelectron. 2018 Jun 25;117:501-507. doi: 10.1016/j.bios.2018.06.047. [Epub ahead of print] PubMed PMID: 29982120.

11: Sharifi-Rad J, Tayeboon GS, Niknam F, Sharifi-Rad M, Mohajeri M, Salehi B, Iriti M, Sharifi-Rad M. Veronica persica Poir. extract - antibacterial, antifungal and scolicidal activities, and inhibitory potential on acetylcholinesterase, tyrosinase, lipoxygenase and xanthine oxidase. Cell Mol Biol (Noisy-le-grand). 2018 Jun 25;64(8):50-56. PubMed PMID: 29981683.

12: Masuzaki H, Kozuka C, Okamoto S, Yonamine M, Tanaka H, Shimabukuro M. Brown rice-specific γ-oryzanol as a promising prophylactic avenue to protect against diabetes mellitus and obesity disease in humans. J Diabetes Investig. 2018 Jul 6. doi: 10.1111/jdi.12892. [Epub ahead of print] Review. PubMed PMID: 29978570.

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16: Fukuyama Y, Hidaka K, Masuda A, Masuda T. Novel Xanthine Oxidase (XO) inhibitory phenylindanes produced by thermal reaction of caffeic acid. Biosci Biotechnol Biochem. 2018 Jul 2:1-4. doi: 10.1080/09168451.2018.1491287. [Epub ahead of print] PubMed PMID: 29961419.

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18: Zhou Q, Huang G, Yu X, Xu W. A Novel Approach to Estimate ROS Origination by Hyperbaric Oxygen Exposure, Targeted Probes and Specific Inhibitors. Cell Physiol Biochem. 2018 Jun 28;47(5):1800-1808. doi: 10.1159/000491061. [Epub ahead of print] PubMed PMID: 29953977.

19: Shih CH, Lee YC. Impaired retinal pigment epithelium in paclitaxel-induced macular edema: A case report. Medicine (Baltimore). 2018 Jun;97(26):e11229. doi: 10.1097/MD.0000000000011229. PubMed PMID: 29952984.

20: Zhong LL, Song YQ, Tian XY, Cao H, Ju KJ. Level of uric acid and uric acid/creatinine ratios in correlation with stage of Parkinson disease. Medicine (Baltimore). 2018 Jun;97(26):e10967. doi: 10.1097/MD.0000000000010967. PubMed PMID: 29952939.