WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461020

CAS#: 60254-95-7

Description: 5-Hydroxymebendazole is a biochemical.

Chemical Structure

CAS# 60254-95-7

Theoretical Analysis

MedKoo Cat#: 461020
Name: 5-Hydroxymebendazole
CAS#: 60254-95-7
Chemical Formula: C16H15N3O3
Exact Mass: 297.1113
Molecular Weight: 297.31
Elemental Analysis: C, 64.64; H, 5.09; N, 14.13; O, 16.14

Price and Availability

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10.0mg USD 420.0 2 Weeks
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Synonym: 5-Hydroxymebendazole; R 19167; R-19167; R19167;

IUPAC/Chemical Name: methyl (5-(hydroxy(phenyl)methyl)-1H-benzo[d]imidazol-2-yl)carbamate


InChi Code: InChI=1S/C16H15N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9,14,20H,1H3,(H2,17,18,19,21)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 297.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Oosterhuis B, Wetsteyn JC, van Boxtel CJ. Liquid chromatography with electrochemical detection for monitoring mebendazole and hydroxymebendazole in echinococcosis patients. Ther Drug Monit. 1984;6(2):215-20. PubMed PMID: 6740740.

2: Gupta S, Srivastava JK, Jain MK, Katiyar JC, Singh J, Bhakuni DS. Efficacy of methyl 5(6)-(alpha-hydroxyphenylmethyl) benzimidazole-2-carbamate, a metabolite of mebendazole, against developing forms of experimental helminth parasites. Indian J Exp Biol. 1991 Jul;29(7):645-8. PubMed PMID: 1794854.

3: De Ruyck H, Daeseleire E, De Ridder H. Development and validation of a liquid chromatography-electrospray tandem mass spectrometry method for mebendazole and its metabolites hydroxymebendazole and aminomebendazole in sheep liver. Analyst. 2001 Dec;126(12):2144-8. PubMed PMID: 11814193.

4: Gupta S, Srivastava JK, Katiyar JC, Singh J, Bhakuni DS. Anthelmintic activity of methyl 5(6)-(alpha-hydroxyphenyl methyl) benzimidazole-2-carbamate, a metabolite of mebendazole. Indian J Exp Biol. 1987 Dec;25(12):871-3. PubMed PMID: 3453816.

5: Iosifidou EG, Haagsma N, Olling M, Boon JH, Tanck MW. Residue study of mebendazole and its metabolites hydroxy-mebendazole and amino-mebendazole in eel (Anguilla anguilla) after bath treatment. Drug Metab Dispos. 1997 Mar;25(3):317-20. PubMed PMID: 9172949.

6: Jain MK, Gupta S, Katiyar JC, Singh SP, Srivastava VM. Alterations in metabolic activity of Cysticercus fasciolaris on some anthelmintic treatments. Indian J Exp Biol. 1992 Apr;30(4):320-3. PubMed PMID: 1459601.