WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563290
CAS#: 554431-74-2
Description: JNJ-17148066 is an estrogen receptor ESR1 agonist.
MedKoo Cat#: 563290
Name: JNJ-17148066
CAS#: 554431-74-2
Chemical Formula: C30H31NO5
Exact Mass: 485.2202
Molecular Weight: 485.58
Elemental Analysis: C, 74.21; H, 6.44; N, 2.88; O, 16.47
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: JNJ-17148066; JNJ 17148066; JNJ17148066;
IUPAC/Chemical Name: (R)-8-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1,8-dihydro-2H-benzo[2,3]oxepino[4,5-c]chromene-5,11-diol
InChi Key: OFYZVZJXVRFMIW-SSEXGKCCSA-N
InChi Code: InChI=1S/C30H31NO5/c32-21-7-11-26-27(18-21)35-16-12-25-24-10-6-22(33)19-28(24)36-30(29(25)26)20-4-8-23(9-5-20)34-17-15-31-13-2-1-3-14-31/h4-11,18-19,30,32-33H,1-3,12-17H2/t30-/m1/s1
SMILES Code: OC1=CC(OCC2)=C(C=C1)C3=C2C(C=CC(O)=C4)=C4O[C@@H]3C5=CC=C(OCCN6CCCCC6)C=C5
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 485.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Krejcík Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH. Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase. Arch Microbiol. 2008 Aug;190(2):159-68. doi: 10.1007/s00203-008-0386-2. Epub 2008 May 28. PubMed PMID: 18506422.
