WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584474

CAS#: 28755-03-5

Description: 3CAI is an inhibitor of Akt1 and Akt2 with anticancer activity.

Chemical Structure

CAS# 28755-03-5

Theoretical Analysis

MedKoo Cat#: 584474
Name: 3CAI
CAS#: 28755-03-5
Chemical Formula: C10H8ClNO
Exact Mass: 193.0294
Molecular Weight: 193.63
Elemental Analysis: C, 62.03; H, 4.16; Cl, 18.31; N, 7.23; O, 8.26

Price and Availability

Size Price Availability Quantity
250.0mg USD 260.0 2 Weeks
500.0mg USD 430.0 2 Weeks
1.0g USD 670.0 2 Weeks
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Synonym: 3CAI

IUPAC/Chemical Name: 2-chloro-1-(1H-indol-3-yl)-ethanone


InChi Code: InChI=1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 193.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Kim, D.J., Reddy, K., Kim, M.O., et al. (3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev. Res. (Phila). 4(11), 1842-1851 (2011).

2. Kim, J.-E., and Kang, T.-C. TRPC3- and ETB receptor-mediated PI3K/AKT activation induces vasogenic edema formation following status epilepticus. Brain Res. 1672, 58-64 (2017).


250.0mg / USD 260.0