BW 942C

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MedKoo CAT#: 597820

CAS#: 98311-64-9

Description: BW 942C is an enkephalin-like pentapeptide.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-15. Prices are subject to change without notice.

BW 942C is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 597820
Name: BW 942C
CAS#: 98311-64-9
Chemical Formula: C32H43N7O11S
Exact Mass:
Molecular Weight: 733.79
Elemental Analysis: C, 52.38; H, 5.91; N, 13.36; O, 23.98; S, 4.37

Synonym: BW 942C; BW-942C; BW942C; BW-942-C; Tyr-met-O-gly-4-No2-phe-pro-NH2;

IUPAC/Chemical Name: (2S)-1-((S)-2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)-3-(4-nitrophenyl)propanoyl)-N-(2-amino-4-(methylsulfinyl)butanoyl)pyrrolidine-2-carboxamide acetate


InChi Code: InChI=1S/C30H39N7O9S.C2H4O2/c1-47(46)14-12-22(31)28(41)35-29(42)25-3-2-13-36(25)30(43)24(16-19-4-8-20(9-5-19)37(44)45)34-26(39)17-33-27(40)23(32)15-18-6-10-21(38)11-7-18;1-2(3)4/h4-11,22-25,38H,2-3,12-17,31-32H2,1H3,(H,33,40)(H,34,39)(H,35,41,42);1H3,(H,3,4)/t22?,23-,24-,25-,47?;/m0./s1

SMILES Code: O=C(NC(C(N)CCS(C)=O)=O)[C@H]1N(C([C@H](CC2=CC=C([N+]([O-])=O)C=C2)NC(CNC([C@H](CC3=CC=C(O)C=C3)N)=O)=O)=O)CCC1.CC(O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Boucher BA, Foster TS, Phillips BA, Fleck RJ, Kirksey DF, Cato AE. The acute effects of the enkephalin analogue BW 942C in humans. J Clin Pharmacol. 1987 Feb;27(2):151-4. PubMed PMID: 3119677.

2: Berschneider HM, Martens H, Powell DW. Effect of BW 942C, an enkephalinlike pentapeptide, on sodium and chloride transport in the rabbit ileum. Gastroenterology. 1988 Jan;94(1):127-36. PubMed PMID: 2446944.

3: James MK, Leighton HJ. Naloxazone treatment in the guinea pig ileum in vitro reveals second functional opioid receptor site. J Pharmacol Exp Ther. 1987 Jan;240(1):138-44. PubMed PMID: 3027301.

4: Kumor K, Su TP, Vaupel B, Haertzen C, Johnson RE, Goldberg S. Studies of kappa agonist. NIDA Res Monogr. 1986;67:18-25. PubMed PMID: 3018572.

5: Ericsson CD, DuPont HL, Johnson PC. Nonantibiotic therapy for travelers' diarrhea. Rev Infect Dis. 1986 May-Jun;8 Suppl 2:S202-6. Review. PubMed PMID: 3523716.

6: Kris MG, Gralla RJ, Clark RA, Tyson LB, Groshen S. Control of chemotherapy-induced diarrhea with the synthetic enkephalin BW942C: a randomized trial with placebo in patients receiving cisplatin. J Clin Oncol. 1988 Apr;6(4):663-8. PubMed PMID: 3282034.

7: Mucha RF, Iversen SD. Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat. Brain Res. 1986 Nov 12;397(2):214-24. PubMed PMID: 3026557.

8: Ericsson CD, Johnson PC, DuPont HL, Morgan DR. Role of a novel antidiarrheal agent, BW942C, alone or in combination with trimethoprim-sulfamethoxazole in the treatment of traveler's diarrhea. Antimicrob Agents Chemother. 1986 Jun;29(6):1040-6. PubMed PMID: 3524436; PubMed Central PMCID: PMC180497.

9: Morgan DR, Sellin J, Gutierrez L, DuPont HL, Wood LV. Evaluation of BW942C, a novel antidiarrheal agent, against enterotoxins of Escherichia coli and Vibrio cholerae. Infect Immun. 1985 Jun;48(3):754-8. PubMed PMID: 3838969; PubMed Central PMCID: PMC261252.

10: Vaupel DB, Cone EJ, Johnson RE, Su TP. Kappa opioid partial agonist activity of the enkephalin-like pentapeptide BW942C based on urination and in vitro studies in humans and animals. J Pharmacol Exp Ther. 1990 Jan;252(1):225-34. PubMed PMID: 2153801.