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MedKoo CAT#: 558405

CAS#: 1392443-41-2

Description: VU0455691 is a selective Allosteric Modulators of the M1 Muscarinic Receptor.

Price and Availability

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Pricing updated 2020-10-29. Prices are subject to change without notice.

VU0455691 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 558405
Name: VU0455691
CAS#: 1392443-41-2
Chemical Formula: C24H25N5O3S
Exact Mass: 463.17
Molecular Weight: 463.56
Elemental Analysis: C, 62.19; H, 5.44; N, 15.11; O, 10.35; S, 6.92

Synonym: VU0455691; VU-0455691; VU 0455691;

IUPAC/Chemical Name: [Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone


InChi Code: InChI=1S/C24H25N5O3S/c30-24(28-13-18-11-27(12-19(18)14-28)21-4-7-25-8-5-21)20-15-29(16-20)33(31,32)23-3-1-2-17-10-26-9-6-22(17)23/h1-10,18-20H,11-16H2

SMILES Code: O=C(N1CC(CN(C2=CC=NC=C2)C3)C3C1)C4CN(S(=O)(C5=CC=CC6=C5C=CN=C6)=O)C4

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Melancon BJ, Utley TJ, Sevel C, Mattmann ME, Cheung YY, Bridges TM, Morrison RD, Sheffler DJ, Niswender CM, Daniels JS, Conn PJ, Lindsley CW, Wood MR. Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5035-40. doi: 10.1016/j.bmcl.2012.06.018. Epub 2012 Jun 15. PubMed PMID: 22749871; PubMed Central PMCID: PMC3883446.