WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597747
CAS#: 130582-12-6
Description: Jmv 332 is a cyclic analog of the C-terminal hexapeptide of CCK. Jmv 332 functions as CCK/gastrin receptor agonist.
MedKoo Cat#: 597747
Name: Jmv 332
CAS#: 130582-12-6
Chemical Formula: C44H58N10O11
Exact Mass: 902.4287
Molecular Weight: 903.0
Elemental Analysis: C, 58.52; H, 6.47; N, 15.51; O, 19.49
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Synonym: Jmv 332; Jmv-332; Jmv332;
IUPAC/Chemical Name: (3S,6S,9S,15S,Z)-9-((1H-indol-3-yl)methyl)-15-acetamido-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-6-(4-aminobutyl)-5,8,11,14,21,24-hexaoxo-4,7,10,13,20-pentaazatetracos-22-enoic acid
InChi Key: ZMIFULRIGOBNGJ-ZTDUOXEXSA-N
InChi Code: 1S/C44H58N10O11/c1-27(56)50-32(17-8-10-20-47-37(57)18-11-21-55)41(62)49-26-38(58)51-35(23-29-25-48-31-15-6-5-14-30(29)31)43(64)52-33(16-7-9-19-45)42(63)54-36(24-39(59)60)44(65)53-34(40(46)61)22-28-12-3-2-4-13-28/h2-6,11-15,18,21,25,32-36,48H,7-10,16-17,19-20,22-24,26,45H2,1H3,(H2,46,61)(H,47,57)(H,49,62)(H,50,56)(H,51,58)(H,52,64)(H,53,65)(H,54,63)(H,59,60)/b18-11-/t32-,33-,34-,35-,36-/m0/s1
SMILES Code: O=C(C)N[C@@H](CCCCNC(/C=C\C=O)=O)C(NCC(N[C@@H](Cc(c[nH]1)c2c1cccc2)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](Cc3ccccc3)C(N)=O)=O)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 903.0 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Witte DG, Nadzan AM, Martinez J, Rodriguez M, Lin CW. Characterization of the novel CCK analogs JMV-180, JMV-320, and JMV-332 in H345 cells. Peptides. 1992 Nov-Dec;13(6):1227-32. PubMed PMID: 1337381.
