Jmv 176

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597744

CAS#: 119068-32-5

Description: Jmv 176 is a CCK agonist when first given, becomes cholecystokinin antagonist after 3-4 hours.

Chemical Structure

Jmv 176
CAS# 119068-32-5

Theoretical Analysis

MedKoo Cat#: 597744
Name: Jmv 176
CAS#: 119068-32-5
Chemical Formula: C53H70N8O15S
Exact Mass: 1090.4681
Molecular Weight: 1091.24
Elemental Analysis: C, 58.34; H, 6.47; N, 10.27; O, 21.99; S, 2.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Jmv 176; Jmv-176; Jmv176; Boc-tyr(SO3)-nle-psi-(coch2)-gly-trp-nle-asp-phe-NH2;

IUPAC/Chemical Name: (6S,9S,15S,18S,21S)-15-((1H-indol-3-yl)methyl)-21-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-9,18-dibutyl-2,2-dimethyl-4,7,10,13,16,19-hexaoxo-6-(4-(sulfooxy)benzyl)-3-oxa-5,8,14,17,20-pentaazatricosan-23-oic acid


InChi Code: InChI=1S/C53H70N8O15S/c1-6-8-18-38(57-49(68)41(61-52(71)75-53(3,4)5)28-33-21-23-35(24-22-33)76-77(72,73)74)44(62)25-26-45(63)56-42(29-34-31-55-37-20-14-13-17-36(34)37)50(69)58-39(19-9-7-2)48(67)60-43(30-46(64)65)51(70)59-40(47(54)66)27-32-15-11-10-12-16-32/h10-17,20-24,31,38-43,55H,6-9,18-19,25-30H2,1-5H3,(H2,54,66)(H,56,63)(H,57,68)(H,58,69)(H,59,70)(H,60,67)(H,61,71)(H,64,65)(H,72,73,74)/t38-,39-,40-,41-,42-,43-/m0/s1

SMILES Code: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CCC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC4=CC=C(OS(=O)(O)=O)C=C4)=O)CCCC)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 1091.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Gourch A, Orosco M, Rodriguez M, Martinez J, Jacquot C, Cohen Y. A cholecystokinin agonist/antagonist according to dose and time of action: effect on food intake. Neuropeptides. 1990 Dec;17(4):187-91. PubMed PMID: 2093151.