WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597744
CAS#: 119068-32-5
Description: Jmv 176 is a CCK agonist when first given, becomes cholecystokinin antagonist after 3-4 hours.
MedKoo Cat#: 597744
Name: Jmv 176
CAS#: 119068-32-5
Chemical Formula: C53H70N8O15S
Exact Mass: 1090.4681
Molecular Weight: 1091.24
Elemental Analysis: C, 58.34; H, 6.47; N, 10.27; O, 21.99; S, 2.94
This product is not in stock, which may be available by custom synthesis.
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Synonym: Jmv 176; Jmv-176; Jmv176; Boc-tyr(SO3)-nle-psi-(coch2)-gly-trp-nle-asp-phe-NH2;
IUPAC/Chemical Name: (6S,9S,15S,18S,21S)-15-((1H-indol-3-yl)methyl)-21-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-9,18-dibutyl-2,2-dimethyl-4,7,10,13,16,19-hexaoxo-6-(4-(sulfooxy)benzyl)-3-oxa-5,8,14,17,20-pentaazatricosan-23-oic acid
InChi Key: NCFOOKGNFFMGDK-KHVQSSSXSA-N
InChi Code: InChI=1S/C53H70N8O15S/c1-6-8-18-38(57-49(68)41(61-52(71)75-53(3,4)5)28-33-21-23-35(24-22-33)76-77(72,73)74)44(62)25-26-45(63)56-42(29-34-31-55-37-20-14-13-17-36(34)37)50(69)58-39(19-9-7-2)48(67)60-43(30-46(64)65)51(70)59-40(47(54)66)27-32-15-11-10-12-16-32/h10-17,20-24,31,38-43,55H,6-9,18-19,25-30H2,1-5H3,(H2,54,66)(H,56,63)(H,57,68)(H,58,69)(H,59,70)(H,60,67)(H,61,71)(H,64,65)(H,72,73,74)/t38-,39-,40-,41-,42-,43-/m0/s1
SMILES Code: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CCC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC4=CC=C(OS(=O)(O)=O)C=C4)=O)CCCC)=O)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 1091.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Gourch A, Orosco M, Rodriguez M, Martinez J, Jacquot C, Cohen Y. A cholecystokinin agonist/antagonist according to dose and time of action: effect on food intake. Neuropeptides. 1990 Dec;17(4):187-91. PubMed PMID: 2093151.
