L 363564

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597736

CAS#: 86153-46-0

Description: L 363564 is a kidney renin inhibitor.


Price and Availability

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L 363564 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 597736
Name: L 363564
CAS#: 86153-46-0
Chemical Formula: C54H76N12O10
Exact Mass: 1052.5807
Molecular Weight: 1053.27
Elemental Analysis: C, 61.58; H, 7.27; N, 15.96; O, 15.19


Synonym: L 363564; L-363564; L363564; L-363,564; L 363,564; L363,564; Boc-his-pro-phe-his-statine-leu-phe-NH2;

IUPAC/Chemical Name: tert-butyl (1-(2-((13-((1H-imidazol-5-yl)methyl)-1-amino-2-benzyl-9-hydroxy-5,10-diisobutyl-1,4,7,12,15-pentaoxo-17-phenyl-3,6,11,14-tetraazaheptadecan-16-yl)carbamoyl)pyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)carbamate

InChi Key: LIAZNMWGUZOVRC-UHFFFAOYSA-N

InChi Code: 1S/C54H76N12O10/c1-32(2)21-38(45(67)27-46(68)60-40(22-33(3)4)48(70)62-39(47(55)69)23-34-15-10-8-11-16-34)61-50(72)42(25-36-28-56-30-58-36)63-49(71)41(24-35-17-12-9-13-18-35)64-51(73)44-19-14-20-66(44)52(74)43(26-37-29-57-31-59-37)65-53(75)76-54(5,6)7/h8-13,15-18,28-33,38-45,67H,14,19-27H2,1-7H3,(H2,55,69)(H,56,58)(H,57,59)(H,60,68)(H,61,72)(H,62,70)(H,63,71)(H,64,73)(H,65,75)

SMILES Code: CC(CC(NC(C(NC(C(NC(C1CCCN1C(C(NC(OC(C)(C)C)=O)Cc2[nH]cnc2)=O)=O)Cc3ccccc3)=O)Cc4[nH]cnc4)=O)C(O)CC(NC(C(NC(C(N)=O)Cc5ccccc5)=O)CC(C)C)=O)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Foundling SI, Cooper J, Watson FE, Cleasby A, Pearl LH, Sibanda BL, Hemmings A, Wood SP, Blundell TL, Valler MJ, et al. High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes. Nature. 1987 May 28-Jun 3;327(6120):349-52. PubMed PMID: 3295561.